Results 101 to 110 of about 226,986 (311)

Principal bundles under reductive groups [PDF]

open access: yesarXiv, 2015
Let $k$ be a field of characteristic $0$. We consider principal bundles over a $k$-scheme with reductive structure group (not necessarily of finite type). It is showm in particular that for $k$ algebraically closed there exists on any complete connected $k$-scheme a universal such bundle.
arxiv  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

The curvature object for fundamental-group connection associated with congruence of hypercentred planes

open access: yesДифференциальная геометрия многообразий фигур, 2018
The congruence of hypercentred planes is investigated in n-di­men­sional projective space. The congruence is a holonomic smooth manifold. It is proved that curvature object for the fundamental-group connection in the principal fibre bundle associated ...
A. Vyalova
doaj  

Parallel Connections Over Symmetric Spaces [PDF]

open access: yesarXiv, 1997
Let M be a simply connected Riemannian symmetric space, with at most one flat direction. We show that every Riemannian (or unitary) vector bundle with parallel curvature over M is an associated vector bundle of a canonical principal bundle, with the connection inherited from the principal bundle.
arxiv  

Connections and Frame Bundle Reductions [PDF]

open access: yesarXiv, 2020
In general relativity, the gravitational potential is represented by the Levi-Civita connection, the only symmetric connection preserving the metric. On a differentiable manifold, a metric identifies with an orthogonal structure, defined as a Lorentz reduction of the frame bundle.
arxiv  

A Tannakian approach to dimensional reduction of principal bundles [PDF]

open access: yes, 2016
Let $P$ be a parabolic subgroup of a connected simply connected complex semisimple Lie group $G$. Given a compact K\"ahler manifold $X$, the dimensional reduction of $G$-equivariant holomorphic vector bundles over $X\times G/P$ was carried out by the first and third authors.
arxiv   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Connective structure for principal gerbes [PDF]

open access: yesarXiv, 2005
In this paper we generalize the notion of connective structure defined by Pierre Deligne to gerbes bounded by the automorphisms group of a principal bundle.
arxiv  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

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