Results 71 to 80 of about 1,438,169 (315)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Micropolar Modeling of Shear Wave Dispersion in Marine Sediments and Deep Earth Materials: Deriving Scaling Laws

Geosciences
We draw connections between eight different theories used to describe microscopic (atomic) and macroscopic (seismological) scales. In particular, we show that all these different theories belong to a particular case of a single partial differential ...
Rafael Abreu
doaj   +1 more source

The image of society in the theory of Islamic literature

آداب الكوفة, 2011
One of the important principles in the theory of Islamic literature is to look at any social phenomenon through its true location in the context of the social system that is subject to the divine laws that govern the movement of history and ...
عبد الكريم المحمود
doaj   +1 more source

Projective module description of the q-monopole

, 1998
The Dirac q-monopole connection is used to compute projector matrices of quantum Hopf line bundles for arbitrary winding number. The Chern-Connes pairing of cyclic cohomology and K-theory is computed for the winding number -1.
Hajac, P. M., Majid, S.
core   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Analysis of Approximation by Linear Operators on Variable Lρp(·) Spaces and Applications in Learning Theory

Abstract and Applied Analysis, 2014
This paper is concerned with approximation on variable Lρp(·) spaces associated with a general exponent function p and a general bounded Borel measure ρ on an open subset Ω of Rd. We mainly consider approximation by Bernstein type linear operators. Under
Bing-Zheng Li, Ding-Xuan Zhou
doaj   +1 more source

Isoperimetric Inequalities in Simplicial Complexes

, 2013
In graph theory there are intimate connections between the expansion properties of a graph and the spectrum of its Laplacian. In this paper we define a notion of combinatorial expansion for simplicial complexes of general dimension, and prove that ...
A. Duval, A. Gundert, A. Gundert, A. Lubotzky, A. Lubotzky, A. Lubotzky, A. Marcus, A. Nilli, A. Żuk, B. Eckmann, D. Dotterrer, D. Puder, D. W. Matula, F. Chung, F. R. K. Chung, H. Garland, I. Newman, J. Cheeger, J. Dodziuk, J. Fox, J. Friedman, J. Friedman, J. Friedman, J. Matoušsek, J. Pach, J. Steenbergen, M. Blum, N. Alon, N. Alon, N. Alon, N. Linial, O. Parzanchevski, Ori Parzanchevski, P. Buser, P. Erdős, P. Erdős, R. Aharoni, R. Beigel, R. I. Oliveira, R. M. Tanner, R. Meshulam, Ran J. Tessler, Ron Rosenthal, S. Hoory, S. Janson, T. Tao, W. Kook, Y. Bilu   +47 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Information and Physics

Information, 2012
In this paper I discuss the question: what comes first, physics or information? The two have had a long-standing, symbiotic relationship for almost a hundred years out of which we have learnt a great deal.
Vlatko Vedral
doaj   +1 more source

Bundle geometry of the connection space, covariant Hamiltonian formalism, the problem of boundaries in gauge theories, and the dressing field method

Journal of High Energy Physics, 2021
We take advantage of the principal bundle geometry of the space of connections to obtain general results on the presymplectic structure of two classes of (pure) gauge theories: invariant theories, and non-invariant theories satisfying two restricting ...
J. François
doaj   +1 more source