Results 61 to 70 of about 15,852,357 (241)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

BPS Wilson loops in N $$ \mathcal{N} $$ ≥ 2 superconformal Chern-Simons-matter theories

Journal of High Energy Physics, 2018
In N $$ \mathcal{N} $$ ≥ 2 superconformal Chern-Simons-matter theories we construct the infinite family of Bogomol’nyi-Prasad-Sommerfield (BPS) Wilson loops featured by constant parametric couplings to scalar and fermion matter, including both line ...
Andrea Mauri, Hao Ouyang, Silvia Penati, Jun-Bao Wu, Jiaju Zhang   +4 more
doaj   +1 more source

Chapter 18 of the General Theory “Further Analysed”: The Theory of Economics as A Method [PDF]

In 1987, Greenwald and Stiglitz accused Keynes’s summary of the General Theory in chapter 18 of relying upon “neoclassical and Marshallian tools”. A number of contributions have on the contrary emphasized the methodological importance of this chapter ...
Mario A. Cedrini, Anna M. Carabelli
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Castles and Other Fortifications Versus Martial Art

Sport i Turystyka
From the perspective of the General Theory of Fighting Arts and the knowledge of defensive architecture and history, selected examples ofmedieval art of fortifications were shown.
Wojciech J. Cynarski
doaj   +1 more source

Sentential and morphological negations: an analysis of theses from Cognitive Linguistics based on iconic models [PDF]

Studii de Lingvistica, 2019
Cognitive Linguistics is an important approach to language and cognition that gives relevant arguments and theses on topics related to these subject matters.
Miguel López-Astorga
doaj  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Essays on Board of Directors’ External Connections [PDF]

, 2013
The two essays in this dissertation study issues related to the board of directors’ external connections, i.e., social ties to directors and executives of other firms.
Kim, Sehan
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source