Results 41 to 50 of about 15,852,357 (241)

Monad Transformers for Backtracking Search [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
This paper extends Escardo and Oliva's selection monad to the selection monad transformer, a general monadic framework for expressing backtracking search algorithms in Haskell.
Jules Hedges
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Feasibility of a Personal Neuromorphic Emulation

open access: yesEntropy
The representation of intelligence is achieved by patterns of connections among neurons in brains and machines. Brains grow continuously, such that their patterns of connections develop through activity-dependent specification, with the continuing ...
Don M. Tucker, Phan Luu
doaj   +1 more source

The cognitive principles of learning underlying the 5E Model of Instruction

open access: yesInternational Journal of STEM Education, 2022
Over 34 years since its conception, research in educational settings has found evidence for the effectiveness of the 5E Instructional Model. Indeed, several studies have reported evidence of a better conceptual understanding of scientific ideas and ...
Héctor Ruiz-Martín, Rodger W. Bybee
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Laramie Project Epilogue (BSC Connections)

open access: yes, 2009
Article "BSC Theatre joines worldwide event" in BSC Connections (newsletter), vol. 13, no.
BSC Connections
core   +2 more sources

Common neighbours and the local-community-paradigm for topological link prediction in bipartite networks

open access: yesNew Journal of Physics, 2015
Bipartite networks are powerful descriptions of complex systems characterized by two different classes of nodes and connections allowed only across but not within the two classes.
Simone Daminelli   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Analysis of Approximation by Linear Operators on Variable Lρp(·) Spaces and Applications in Learning Theory

open access: yesAbstract and Applied Analysis, 2014
This paper is concerned with approximation on variable Lρp(·) spaces associated with a general exponent function p and a general bounded Borel measure ρ on an open subset Ω of Rd. We mainly consider approximation by Bernstein type linear operators. Under
Bing-Zheng Li, Ding-Xuan Zhou
doaj   +1 more source

The image of society in the theory of Islamic literature

open access: yesآداب الكوفة, 2011
One of the important principles in the theory of Islamic literature is to look at any social phenomenon through its true location in the context of the social system that is subject to the divine laws that govern the movement of history and ...
عبد الكريم المحمود
doaj   +1 more source

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