A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]
Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Bahn, Rebecca S. +3 more
core +1 more source
Modulation of Fibrosis in Systemic Sclerosis by Nitric Oxide and Antioxidants
Systemic sclerosis (scleroderma: SSc) is a multisystem, connective tissue disease of unknown aetiology characterized by vascular dysfunction, autoimmunity, and enhanced fibroblast activity resulting in fibrosis of the skin, heart, and lungs, and ...
Audrey Dooley +2 more
doaj +1 more source
Tissue eosinophilia and eosinophil degranulation in Riedel's invasive fibrous thyroiditis. [PDF]
The etiology of Riedel's invasive fibrous thyroiditis (IFT) has remained obscure. This rare disorder has been confused in the past with the more common fibrous variant of Hashimoto's disease.
Bahn, R. S. +4 more
core +1 more source
Background Hyper IgE syndrome is a rare heterogeneous immunodeficiency syndrome which is characterized by recurrent episodes of cutaneous and respiratory tract infections and development of cold abscesses.
Atefeh Kheyrollahiyan +2 more
doaj +1 more source
The role of endothelin-1 in pulmonary arterial hypertension. [PDF]
Pulmonary arterial hypertension (PAH) is a rare but debilitating disease, which if left untreated rapidly progresses to right ventricular failure and eventually death. In the quest to understand the pathogenesis of this disease differences in the profile,
Chester, AH, Yacoub, MH
core +1 more source
Could the super-pulsed CO2 laser be used for oral excisional biopsies? [PDF]
Background. The main purpose of a biopsy is microscopic examination and diagnosis. Keeping the margins of specimens safe and readable is always fundamental to detecting marginal infiltrations or malignant transformation.
Ambrogiano, Simone +6 more
core +1 more source
Mixed connective tissue disease and severe renal disease – an apparent misconception?
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Filipe Oliveira Pinheiro +3 more
doaj +1 more source
Nitric Oxide Manipulation: A Therapeutic Target for Peripheral Arterial Disease?
Peripheral Arterial Disease (PAD) is a cause of significant morbidity and mortality in the Western world. Risk factor modification and endovascular and surgical revascularisation are the main treatment options at present. However, a significant number of
Gareth Williams +5 more
doaj +1 more source
Determining the Frequency of Macroamylasemia in Patients with Hyperamylasemia using PEG Precipitation Method [PDF]
Introduction: The term acute abdomen refers to severe and sudden abdominal pain requiring urgent reorganisation. One of the factors causing acute abdomen is acute pancreatitis, which needs immediate measurements.
Amir Vahedi +6 more
doaj +1 more source
Rethinking the role of alpha toxin in Clostridium perfringens-associated enteric diseases : a review on bovine necro-haemorrhagic enteritis [PDF]
Bovine necro-haemorrhagic enteritis is an economically important disease caused by Clostridium perfringens type A strains. The disease mainly affects calves under intensive rearing conditions and is characterized by sudden death associated with small ...
Deprez, Piet +6 more
core +3 more sources

