Use of Patterned Collagen Coated Slides to Study Normal and Scleroderma Lung Fibroblast Migration
Scientific Reports, 2017 Systemic sclerosis (SSc) is a spreading fibrotic disease affecting the skin and internal organs. We aimed to model pathogenic fibroblast migration in SSc in order to identify enhancing factors, measure the effect of migrating cells on underlying ...
Bahja Ahmed Abdi +12 more
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Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
, 1996 To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E. +2 more
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Malignancy in ankylosing spondylitis: a cross-sectional analysis of a large population database
BMC Rheumatology, 2022 Background Increased cancer-risk has been reported with rheumatoid arthritis and systemic lupus erythematosus, but the risk is poorly studied in ankylosing spondylitis (AS).
Mohamad Bittar +3 more
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A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]
, 1994 Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Bahn, Rebecca S. +3 more
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Mixed connective tissue disease, undifferentiated connective tissue disease and overlap syndromes
Alʹmanah Kliničeskoj Mediciny, 2019 Systemic lupus erythematosus, systemic sclerosis, inflammatory myopathy and rheumatoid arthritis are systemic connective tissue disorders which are characterized by heterogeneous clinical symptoms and variable course. To date, updated diagnostic criteria
R. T. Alekperov
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Connective tissue degeneration: Mechanisms of palmar fascia degeneration (Dupuytren’s disease) [PDF]
, 2016 Dupuytren’s disease is a connective tissue disorder of the hand causing excessive palmar fascial fibrosis with associated finger contracture and disability.
Chojnowski, A. +8 more
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Mixed connective tissue disease
Современная ревматология, 2019 Mixed connective tissue disease (MCTD), also known as Sharp's syndrome, is a rare systemic connective tissue disorder that characterized by a combination of some features of systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis ...
R. U. Shayakhmetova, L. P. Ananyeva
doaj +1 more source
Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]
, 2006 It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
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Modulation of Fibrosis in Systemic Sclerosis by Nitric Oxide and Antioxidants
Cardiology Research and Practice, 2012 Systemic sclerosis (scleroderma: SSc) is a multisystem, connective tissue disease of unknown aetiology characterized by vascular dysfunction, autoimmunity, and enhanced fibroblast activity resulting in fibrosis of the skin, heart, and lungs, and ...
Audrey Dooley +2 more
doaj +1 more source
Undifferentiated connective tissue disease: a seven-center cross-sectional study of 184 patients [PDF]
, 2009 The purpose of this study was to characterize the clinical and serological features of a large cohort of patients with antinuclear antibody (ANA) positive undifferentiated connective tissue disease (UCTD).
Barcelos, A +10 more
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