Results 31 to 40 of about 407,383 (333)
Toll-like receptors (TLRs) are key receptors of the innate immune system which are expressed on immune and nonimmune cells. They are activated by both pathogen-associated molecular patterns and endogenous ligands.
Hemanshu Patel +5 more
doaj +1 more source
Rituximab in autoimmune connective tissue disease-associated interstitial lung disease [PDF]
Objective. CTD-associated interstitial lung disease (ILD) often fails to respond to conventional immunomodulatory agents. There is now considerable interest in the use of rituximab in systemic autoimmune CTD in patients refractory to standard treatments.
Adamali, Huzaifa +7 more
core +2 more sources
Cutaneous mucinosis in mixed connective tissue disease* [PDF]
Cutaneous mucinosis is a group of conditions involving an accumulation of mucin or glycosaminoglycan in the skin and its annexes. It is described in some connective tissue diseases but never in association with mixed connective tissue disease.
Maria Helena Sampaio Favarato +5 more
doaj +1 more source
Mixed connective tissue disease — enigma variations? [PDF]
In 1972, Sharp and colleagues described a new autoimmune rheumatic disease which they called mixed connective tissue disease (MCTD), characterized by overlapping features of systemic sclerosis (SSc), systemic lupus erythematosus (SLE), polymyositis ...
Ciang, NCO, Isenberg, DA, Pereira, N
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Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li +6 more
wiley +1 more source
IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cells. [PDF]
Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling.
Fehrholz, Markus +6 more
core +10 more sources
Rationale: The prognosis of pulmonary arterial hypertension is poor, especially amongst patients with connective tissue disease related pulmonary arterial hypertension.
Katharine R. Clapham +3 more
doaj +1 more source
The role of cross-training in swim-related injuries in master’s swimmers [PDF]
Orthopedic injuries often interfere with Masters athletes’ pursuit of better performance and might place economic burden on these athletes. PURPOSE: We determined if the incidence of injuries increases with age and the economic burden associated with ...
Baker, Brett Donovan, Jr.
core +1 more source
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed +5 more
wiley +1 more source
Medical geography and its contribution to the aetiology of rare systemic connective tissue diseases : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Geography at Massey University [PDF]
This thesis is in two interrelated parts. Part One traced the historical development of medical geography since the idea of applying a geographical perspective to medical problems was first mooted in 4 B.C.
Borman, Graham Barry
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