Results 31 to 40 of about 407,383 (333)

Toll-Like Receptors in Ischaemia and Its Potential Role in the Pathophysiology of Muscle Damage in Critical Limb Ischaemia

open access: yesCardiology Research and Practice, 2012
Toll-like receptors (TLRs) are key receptors of the innate immune system which are expressed on immune and nonimmune cells. They are activated by both pathogen-associated molecular patterns and endogenous ligands.
Hemanshu Patel   +5 more
doaj   +1 more source

Rituximab in autoimmune connective tissue disease-associated interstitial lung disease [PDF]

open access: yes, 2016
Objective. CTD-associated interstitial lung disease (ILD) often fails to respond to conventional immunomodulatory agents. There is now considerable interest in the use of rituximab in systemic autoimmune CTD in patients refractory to standard treatments.
Adamali, Huzaifa   +7 more
core   +2 more sources

Cutaneous mucinosis in mixed connective tissue disease* [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2013
Cutaneous mucinosis is a group of conditions involving an accumulation of mucin or glycosaminoglycan in the skin and its annexes. It is described in some connective tissue diseases but never in association with mixed connective tissue disease.
Maria Helena Sampaio Favarato   +5 more
doaj   +1 more source

Mixed connective tissue disease — enigma variations? [PDF]

open access: yes, 2017
In 1972, Sharp and colleagues described a new autoimmune rheumatic disease which they called mixed connective tissue disease (MCTD), characterized by overlapping features of systemic sclerosis (SSc), systemic lupus erythematosus (SLE), polymyositis ...
Ciang, NCO, Isenberg, DA, Pereira, N
core  

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cells. [PDF]

open access: yes, 2012
Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling.
Fehrholz, Markus   +6 more
core   +10 more sources

Reduced RVSWI Is Associated With Increased Mortality in Connective Tissue Disease Associated Pulmonary Arterial Hypertension

open access: yesFrontiers in Cardiovascular Medicine, 2020
Rationale: The prognosis of pulmonary arterial hypertension is poor, especially amongst patients with connective tissue disease related pulmonary arterial hypertension.
Katharine R. Clapham   +3 more
doaj   +1 more source

The role of cross-training in swim-related injuries in master’s swimmers [PDF]

open access: yes, 2019
Orthopedic injuries often interfere with Masters athletes’ pursuit of better performance and might place economic burden on these athletes. PURPOSE: We determined if the incidence of injuries increases with age and the economic burden associated with ...
Baker, Brett Donovan, Jr.
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Medical geography and its contribution to the aetiology of rare systemic connective tissue diseases : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Geography at Massey University [PDF]

open access: yes, 1975
This thesis is in two interrelated parts. Part One traced the historical development of medical geography since the idea of applying a geographical perspective to medical problems was first mooted in 4 B.C.
Borman, Graham Barry
core  

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