Results 91 to 100 of about 472,288 (373)
RheumatologyIntroduction Antiphospholipid syndrome (APS) manifests with thrombosis and pregnancy losses and may significantly impair the health-related quality of life (HRQoL).
Ewa Haladyj +3 more
doaj +1 more source
IL-1β Inhibits Human Osteoblast Migration
Molecular Medicine, 2013 Bone has a high capacity for self-renewal and repair. Prolonged local secretion of interleukin 1β (IL-1β), however, is known to be associated with severe bone loss and delayed fracture healing.
Nina-Emily Hengartner +3 more
doaj +1 more source
An Empirical Bayes Approach for Multiple Tissue eQTL Analysis [PDF]
arXiv, 2013 Expression quantitative trait loci (eQTL) analyses, which identify genetic markers associated with the expression of a gene, are an important tool in the understanding of diseases in human and other populations. While most eQTL studies to date consider the connection between genetic variation and expression in a single tissue, complex, multi-tissue ...
arxiv
Host reaction in paratenic fish hosts against 3rd stage larvae of Anguillicola crassus [PDF]
, 1996 Many fish species of Lake Balaton (Hungary) serve as paratenic hosts for the 3rd stage larvae of the eel parasite Anguillicola crassus. The incidence oi different phases of the host reaction varies with paratenic fish host but its nature is basically the
Molnár, Kálmán +2 more
core +1 more source
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Frontiers in Molecular Biosciences, 2020 ObjectiveAmino acids (AA) and their derivatives play an integral role in the synthesis of structural and regulatory elements in human organisms and therefore pathologies such as systemic sclerosis that may alter the blood pattern of these compounds. This
Zaneta Smolenska +5 more
doaj +1 more source
The pathogenesis of tendinopathy. A molecular perspective [PDF]
, 2004 There are many publications that discuss the aetiology, diagnosis and treatment of the various forms of tendinopathy, but few are based on conclusive scientific evidence.
Riley, GP
core +1 more source
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source