Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim+3 more
wiley +1 more source
A case of systemic urticarial vasculitis in the patient with mixed connective tissue disease.
Toshiaki Shibasaki+5 more
openalex +2 more sources
MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover [PDF]
Kenn Holmbeck+11 more
openalex +1 more source
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang+6 more
wiley +1 more source
Antifibrillarin autoantibodies present in systemic sclerosis and other connective tissue diseases interact with similar epitopes. [PDF]
Kuppuswamy N. Kasturi+3 more
openalex +1 more source
Ophthalmologic Implications of Connective Tissue Diseases: A Comprehensive Review of Current Knowledge and Innovations. [PDF]
Pawar YB, Thool AR.
europepmc +1 more source
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
An autopsy case of mixed connective tissue disease associated with viral myocarditis.
Shuichi Kaneko+7 more
openalex +2 more sources
The role of immune cells in the pathogenesis of connective tissue diseases-associated pulmonary arterial hypertension. [PDF]
Li Z, Ma J, Wang X, Zhu L, Gan Y, Dai B.
europepmc +1 more source