Results 51 to 60 of about 4,100,336 (288)

Improved approximation algorithms for degree-bounded network design problems with node connectivity requirements [PDF]

open access: yes, 2014
We consider degree bounded network design problems with element and vertex connectivity requirements. In the degree bounded Survivable Network Design (SNDP) problem, the input is an undirected graph G = (V, E) with weights w(e) on the edges and degree ...
Ali Vakilian   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Topological Indices of the Pent-Heptagonal Nanosheets VC5C7 and HC5C7

open access: yesAdvances in Materials Science and Engineering, 2019
In this paper, we computed the topological indices of pent-heptagonal nanosheet. Formulas for atom-bond connectivity index, fourth atom-bond connectivity index, Randić connectivity index, sum-connectivity index, first Zagreb index, second Zagreb index ...
Fei Deng   +4 more
doaj   +1 more source

The product connectivity Banhatti index of a graph

open access: yesDiscussiones Mathematicae Graph Theory, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
H. S. Boregowda   +2 more
openaire   +3 more sources

Evaluation of a surface hydrological connectivity index in agricultural catchments

open access: yes, 2013
Identification of surface hydrological connectivity at scales where critical source areas (CSAs) can be managed is fundamental to achieving effective management of phosphorus loss in agricultural catchments. This study investigated the potential for the '
Melland, A. R.   +8 more
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Eccentric Connectivity Index of Strongly Connected Digraphs

open access: yesCoRR
Let $G = (V, E)$ be a graph with non-empty set of vertices $V$ and set of edges $E$. The \emph{eccentric connectivity index} of the graph $G$ is defined as $$\displaystyle{ξ^C(G) = \sum_{u \in V} d_u \;ecc(u)}$$ where $d_u$ is the degree and $ecc(u)$ is the eccentricity of the vertex $u \in V$.
Vysakh Chakooth   +2 more
openaire   +2 more sources

Microstate connectivity alterations in patients with early Alzheimer's disease [PDF]

open access: yes, 2015
Electroencephalography (EEG) microstates and brain network are altered in patients with Alzheimer's disease (AD) and discussed as potential biomarkers for AD. Microstates correspond to defined states of brain activity, and their connectivity patterns may
Andreas Monsch (3564989)   +26 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

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