Results 61 to 70 of about 467,517 (284)

Scaling of critical connectivity of mobile ad hoc communication networks

, 2008
In this paper, critical global connectivity of mobile ad hoc communication networks (MAHCN) is investigated. We model the two-dimensional plane on which nodes move randomly with a triangular lattice.
C. E. Perkins, Chen-Ping Zhu, D. J. Watts, K. Christensen, Li Wang, M. C. Gonzalez, M. E. J. Newman, R. M. Anderson, V. Rodoplu, Zhi-Ming Gu   +9 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Measuring airline hub timetable co-ordination and connectivity: definition of a new index and application to a sample of European hubs [PDF]

, 2006
In this paper a new index for measuring the timetable co-ordination of an airline hub is proposed, with application to a sample of European hubs. This index is both quite accurate and easy to use, so that it may prove a useful schedule analysis tool ...
Danesi, Antonio
core   +1 more source

Encoding Multi-Resolution Brain Networks Using Unsupervised Deep Learning

, 2017
The main goal of this study is to extract a set of brain networks in multiple time-resolutions to analyze the connectivity patterns among the anatomic regions for a given cognitive task.
Alchihabi, Abdullah, Antsaklis, Panos, Gupta, Vijay, Rahnama, Arash, Vural, Fatos T. Yarman   +4 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

The Eccentricity Version of Atom-Bond Connectivity Index of Linear Polycene Parallelogram Benzenoid ABC5(P(n,n))

Acta Chimica Slovenica, 2016
Among topological descriptors, connectivity indices are very important and they have a prominent role in chemistry. The atom-bond connectivity index of a connected graph G is defined as ABC(G)= where dv denotes the degree of vertex v of G and the ...
Wei Gao, Mohammad Reza Farahani, Muhammad Kamran Jamil   +2 more
doaj   +1 more source

Brainstem atrophy in focal epilepsy destabilizes brainstem-brain interactions: Preliminary findings. [PDF]

, 2019
BACKGROUND: MR Imaging has shown atrophy in brainstem regions that were linked to autonomic dysfunction in epilepsy patients. The brainstem projects to and modulates the activation state of several wide-spread cortical/subcortical regions.
Bateman, Lisa M., Goldman, Alica M., Laxer, Kenneth D., Mueller, Susanne G., Nei, Maromi   +4 more
core   +1 more source

Bridgeness: A Local Index on Edge Significance in Maintaining Global Connectivity

, 2010
Edges in a network can be divided into two kinds according to their different roles: some enhance the locality like the ones inside a cluster while others contribute to the global connectivity like the ones connecting two clusters.
Adamic L A, Bunde A, Cheng X-Q, Cheng X-Q, Cheng X-Q, Fu-Xin Ren, Hua-Wei Shen, Jaccard P, Lazarsfeld P, Liu W, Lü L, Newman M E J, Salton G, Shen H-W, Stauffer D, Tao Zhou, Xue-Qi Cheng, Zi-Ke Zhang   +17 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source