Results 101 to 110 of about 300,894 (355)

Design and application of a general connector for drainage tube (一种引流管通用连接器的设计与应用)

open access: yes中西医结合护理
Peritoneal irrigation and drainage plays an important role in abdominal surgery. Peritoneal infection, effusion and hematoma may prolong hospital stay and increase the consumption of medical resources.
FAN Chunmei (范春梅)   +1 more
doaj   +1 more source

Nonlinear Analysis of a Bolted Marine Riser Connector Using NASTRAN Substructuring [PDF]

open access: yes, 1984
Results of an investigation of the behavior of a bolted, flange type marine riser connector is reported. The method used to account for the nonlinear effect of connector separation due to bolt preload and axial tension load is described.
Fox, G. L.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Set of connectors for enterprise information system architecture

open access: yesLietuvos Matematikos Rinkinys, 2009
This paper analyses enterprise information system (EIS) design problem. It is showed that current design methodologies do not provide adequate support for the development of EIS.
Lina Bagušytė, Audronė Lupeikienė
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

The connector space reduction mechanism [PDF]

open access: yes
The Connector Space Reduction Mechanism (CSRM) is a simple device that can reduce the number of electromechanical devices on the Payload Interface Adapter/Station Interface Adapter (PIA/SIA) from 4 to 1.
Milam, M. Bruce
core   +1 more source

Connection space reduction mechanism [PDF]

open access: yes, 1992
A connector assembly comprised of two halves, each respectively including a shell type connector subassembly, one being an active half and the other being a passive half is described.
Milam, Malcolm Bruce
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

La généralisation intensionnelle et la généralisation extensionnelle dans l’architecture du discours mathématique [PDF]

open access: yesDiversitate si Identitate Culturala in Europa, 2017
The aim of our study is to define generalization as a logico-semantic relation in as precise as possible and to grasp its specificity in the scientific text.
Cristina-Alice TOMA
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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