Results 111 to 120 of about 308,175 (358)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Connection space reduction mechanism [PDF]
, 1992 A connector assembly comprised of two halves, each respectively including a shell type connector subassembly, one being an active half and the other being a passive half is described.
Milam, Malcolm Bruce
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Current Study on Choke and Kill Line Connector of Subsea BOP Stack
Shiyou jixie, 2016 Choke and kill line connector is the key equipment of subsea blowout preventer stack,of which the core technology is mainly controlled by a few foreign BOP manufacturers.To guarantee our country’s energy security and protect our maritime rights and ...
Hou Guoqing
doaj
Design and application of a general connector for drainage tube (一种引流管通用连接器的设计与应用)
中西医结合护理Peritoneal irrigation and drainage plays an important role in abdominal surgery. Peritoneal infection, effusion and hematoma may prolong hospital stay and increase the consumption of medical resources.
FAN Chunmei (范春梅) +1 more
doaj +1 more source
Aesthetic rehabilitation with multiple loop connectors
Contemporary Clinical Dentistry, 2013 Patients with a missing tooth along with diastema have limited treatment options to restore the edentulous space. The use of a conventional fixed partial denture (FPD) to replace the missing tooth may result in too wide anterior teeth leading to poor ...
Ashish Kalra +2 more
doaj +1 more source
Zipper-type electrical connectors [PDF]
, 1972 Electrical connector is described of zipper-like configuration, in which sequentially interlocking tines serve as electrical contacts or ...
Levoe, C. E.
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Asidentske i sindetske rečenice u Kur'anu
Anali Gazi Husrev-Begove Biblioteke, 2016 U ovome radu govori se o složenim rečenicama sastavljenim od naporednih nezavisnih prostih rečenica u arapskom jeziku prikazanih na primjerima kur’anskoga teksta.
Mustafa Jahić
doaj