Results 111 to 120 of about 1,643,357 (310)
Experimental study on AR fiberglass connectors for bridges made of composite materials
One highly relevant aspect in composite material bridgedesing is the study of the shear connectors to be used.Composite material bridges most commonly comprise acomposite deck resting on steel or reinforced concrete girders.This article analyzes the ...
A. Miravete +7 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Asidentske i sindetske rečenice u Kur'anu
U ovome radu govori se o složenim rečenicama sastavljenim od naporednih nezavisnih prostih rečenica u arapskom jeziku prikazanih na primjerima kur’anskoga teksta.
Mustafa Jahić
doaj
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Design and application of a general connector for drainage tube (一种引流管通用连接器的设计与应用)
Peritoneal irrigation and drainage plays an important role in abdominal surgery. Peritoneal infection, effusion and hematoma may prolong hospital stay and increase the consumption of medical resources.
FAN Chunmei (范春梅) +1 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Current Study on Choke and Kill Line Connector of Subsea BOP Stack
Choke and kill line connector is the key equipment of subsea blowout preventer stack,of which the core technology is mainly controlled by a few foreign BOP manufacturers.To guarantee our country’s energy security and protect our maritime rights and ...
Hou Guoqing
doaj
Aesthetic rehabilitation with multiple loop connectors
Patients with a missing tooth along with diastema have limited treatment options to restore the edentulous space. The use of a conventional fixed partial denture (FPD) to replace the missing tooth may result in too wide anterior teeth leading to poor ...
Ashish Kalra +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source

