Results 101 to 110 of about 1,652,273 (313)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
RADAR-base/radar-helm-charts: radar-upload-source-connector-0.3.1
<p>A Helm chart for RADAR-base upload kafka connector. This is used for reading uploaded data from backend and sending them to Kafka cluster for later processing.</p ...
Joris Borgdorff +4 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Experimental study on AR fiberglass connectors for bridges made of composite materials
One highly relevant aspect in composite material bridgedesing is the study of the shear connectors to be used.Composite material bridges most commonly comprise acomposite deck resting on steel or reinforced concrete girders.This article analyzes the ...
A. Miravete +7 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
jacintacleary-usyd/Percutaneous-Connector: v1.0.0
<p>All files related to reproducing the Percutaneous Connector as described in the EMBC2024 Conference Proceedings.</p ...
jacintacleary-usyd
core +1 more source
Taming Hierarchical Connectors
Building and maintaining complex systems requires good software engineering practices, including code modularity and reuse. The same applies in the context of coordination of complex component-based systems. This paper investigates how to verify properties of complex coordination patterns built hierarchically, i.e., built from composing blocks that are
José Proença, Alexandre Madeira
openaire +5 more sources
Current Study on Choke and Kill Line Connector of Subsea BOP Stack
Choke and kill line connector is the key equipment of subsea blowout preventer stack,of which the core technology is mainly controlled by a few foreign BOP manufacturers.To guarantee our country’s energy security and protect our maritime rights and ...
Hou Guoqing
doaj
Design and application of a general connector for drainage tube (一种引流管通用连接器的设计与应用)
Peritoneal irrigation and drainage plays an important role in abdominal surgery. Peritoneal infection, effusion and hematoma may prolong hospital stay and increase the consumption of medical resources.
FAN Chunmei (范春梅) +1 more
doaj +1 more source

