Results 121 to 130 of about 216,496 (307)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Leakage Research of Split-type Air-conditioner using R290 as Refrigerant

Zhileng xuebao, 2013
The ozone depletion potential (ODP) and global warming potential (GWP) of HCFCs and HFCs are higher than hydrocarbons (HCs). R290 is perfect in environmental protection and energy saving performance.
张网, 杨昭, 王婕, 吕东, 钟志锋   +4 more
doaj  

Analysis of reticulated dome with universal connector

Acta Polytechnica
In order to investigate the stress-strain state of a 4 m diameter reticulated dome model, four series of glued wooden rods were prepared for centric and eccentric compression tests. The tests were carried out in the laboratory of the Department of Metal
Oleksandr Gilodo, Andrii Arsirii, Yuliia Somina   +2 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The association between stent design and patient exercise intensity: structural coupling effects and hemodynamic analysis

Frontiers in Bioengineering and Biotechnology
IntroductionIn-stent restenosis remains a significant challenge in coronary artery interventions. This study aims to explore the relationship between exercise intensity and stent design, focusing on the coupled response of the stent structure and ...
Rui Lv, Daochun Li, Shiwei Zhao, Peng Shu, Jinwu Xiang   +4 more
doaj   +1 more source

Modified RF coaxial connector ends vacuum chamber wiring problem [PDF]

, 1964
A standard radio frequency coaxial connector is modified so that a plastic insulating sleeve can be mounted in the wall of a vacuum chamber.
Weiner, D.
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Heart catheter cable and connector [PDF]

, 1972
Ultraminiature catheter cables that are stiff enough for intravenous insertion yet flexible at the tip, sterilizable, and economical are fabricated entirely from commercially available parts.
Cota, F. L., Harrison, D. R., Sandler, H.   +2 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Study of Innovative Connector for Steel–Concrete Composite Structures

Applied Sciences
The paper presents an analysis of the innovative connector for manufacturing a steel–concrete composite beam. The connector consists of a corrugated metal sheet in the shape of a dovetail and shot nails. The nails are shot through the sheet fold into the
Anna Derlatka, Piotr Lacki, Paweł Kania, Shan Gao   +3 more
doaj   +1 more source