Results 231 to 240 of about 64,299 (311)

Treatment of Epidermal Pathology in a Pediatric Patient With Keratitis–Ichthyosis–Deafness (KID) Syndrome With Topical Mefenamic Acid

Pediatric Dermatology, Volume 43, Issue 1, Page 145-148, January/February 2026.
ABSTRACT Keratitis–ichthyosis–deafness (KID) syndrome is a rare genetic condition typically presenting at birth with ichthyosiform erythroderma and bilateral hearing loss and later progressing to diffuse keratodermatous plaques with scaling. The condition is associated with mutations in the GJB2 gene, which lead to aberrant activation of connexin ...
Radhika Gupta, Alisa Ho, Lars Brichta, Albert C. Yan   +3 more
wiley   +1 more source

Exploring neuronal mechanisms of osteosarcopenia in older adults

The Journal of Physiology, Volume 604, Issue 2, Page 672-688, 15 January 2026.
Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley   +1 more source

Analysis of Trafficking, Stability and Function of Human Connexin 26 Gap Junction Channels with Deafness-Causing Mutations in the Fourth Transmembrane Helix

, 2013
Cinzia Ambrosi, Amy E. Walker, Adam DePriest, Angela C. Cone, Connie Lu, John Badger, I. Martha Skerrett, Gina E. Sosinsky   +7 more
openalex   +2 more sources

Targeting motifs and functional parameters governing the assembly of connexins into gap junctions [PDF]

, 2000
P. E. MARTIN, J. STEGGLES, C. WILSON, Syed Zahid Ahmad, W. H. EVANS   +4 more
openalex   +1 more source

Lipid dependence of connexin-32 gap junction channel conformations. [PDF]

Nat Commun
Lavriha P, Fluri C, Hernández González JE, Korkhov VM.   +3 more
europepmc   +1 more source

Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models

, 2009
Emilie Hoang Dinh, Shoeb Ahmad, Qing Chang, Wenxue Tang, Benjamin C. Stong, Xi Lin   +5 more
openalex   +1 more source

Genomic Structural Equation Modeling Combined With Post‐GWAS Analysis Identifies Two Risk Gene Loci and Functionally Sensitive Genes Associated With Cardiac Conduction Block

Genetics Research , Volume 2026, Issue 1, 2026.
Background Cardiac conduction disorders (CCDs) represent a broad spectrum of severe cardiovascular conditions associated with syncope and sudden cardiac death. Therefore, identification of reliable biomarkers is necessary to significantly improve the diagnostic accuracy and therapeutic outcomes of CCDs. This study analyzed GWAS summary datasets using a
Tongyu Wang, Xinge Miao, Yunlong Xia, Irfan Ahmad   +3 more
wiley   +1 more source

Implication of intracellular chloride channel in extracellular matrix remodeling in pressure‐overloaded mice and patients with dilated cardiomyopathy

Physiological Reports, Volume 14, Issue 1, January 2026.
Abstract Chloride intracellular channels (CLICs) are important in cardiac cellular physiology. We aimed to determine the pathophysiological roles of CLICs in the heart. For this, we analyzed CLIC expression in cardiomyocytes in a mouse transverse aortic constriction (TAC) model to induce cardiac hypertrophy and failure, as well as in ventricular ...
Gaku Oguri, Seitaro Nomura, Takafumi Nakajima, Hironobu Kikuchi, Syotaro Obi, Issei Komuro, Norihiko Takeda, Shigeru Toyoda, Toshiaki Nakajima   +8 more
wiley   +1 more source

Impact of isoflurane anesthesia on astrocyte connexin 30 expression in adult rats and its possible implications for postoperative neurocognitive disorder. [PDF]

Eur J Med Res
Li MY, Zhang XX, Sun XL, Wang ZY, Li J, Zhang XN.   +5 more
europepmc   +1 more source

Extracellular acidity and ATP modulate ion currents in human cumulus cells indicating possible roles as metabolic sensors of the follicular microenvironment

Physiological Reports, Volume 14, Issue 2, January 2026.
Extracellular acidity and ATP modify electrophysiological profile in human cumulus cell subpopulations, characterized by differential functional expression of TRPM5‐like, BKCa and KV1.5 currents. Abstract Cumulus cells (CCs), derived from granulosa cells, play a key role in supporting oocyte maturation and development through bidirectional ...
Andrea Biagini, Rosaria Gentile, Cristina Corbucci, Monica Mariani, Alessandro Favilli, Sandro Gerli, Bernard Fioretti   +6 more
wiley   +1 more source