Results 101 to 110 of about 25,696 (242)

Connexin 43 Delimits Functional Domains of Neurogenic Precursors in the Spinal Cord [PDF]

open access: hybrid, 2008
Raúl E. Russo   +4 more
openalex   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

open access: yesThe Anatomical Record, Volume 309, Issue 2, Page 417-450, February 2026.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna   +16 more
wiley   +1 more source

Astrocytic TCF7L2 Impacts Brain Osmoregulation and Restricts Neuronal Excitability

open access: yesGlia, Volume 74, Issue 2, February 2026.
Astrocytic TCF7L2 impacts extracellular glutamate and glutamine levels. Loss of astrocytic TCF7L2 disrupts extracellular potassium clearance. TCF7L2‐dependent astrocytic changes reduce neuronal excitability. ABSTRACT Astrocytes differentiate and mature during postnatal development, but the molecular mechanisms linking their maturation to neuronal ...
Mariusz Popek   +10 more
wiley   +1 more source

Novel Roles for the Ectoenzyme CD38 in the Maintenance of Transcriptional and Metabolic Homeostasis in Astrocytes

open access: yesGlia, Volume 74, Issue 2, February 2026.
CD38 deficiency influences brain NAD/NAM metabolism. Global CD38 deficiency drives changes in astrocyte mitochondrial, metabolic, senescence, and neurodegenerative‐related genes. CD38 deficiency alters glial reactivity and astrocyte bioenergetics. ABSTRACT CD38 is an ectoenzyme that converts NAD+ to NAM to help maintain bioenergetic homeostasis.
S. Basak   +15 more
wiley   +1 more source

Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała   +3 more
wiley   +1 more source

Salmonella enhance chemosensitivity in tumor through connexin 43 upregulation [PDF]

open access: bronze, 2013
Wen‐Wei Chang   +6 more
openalex   +1 more source

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan   +13 more
wiley   +1 more source

Pathogenic Variants in Mennonites From Southern Brazil: Implications for Preventive Measures in Public Health

open access: yesClinical Genetics, Volume 109, Issue 2, Page 266-276, February 2026.
In 325 exomes of South Brazilian Mennonites, we identified 23 pathogenic variants (P) and 27 likely P, with founder effects identified for 96% of P, whose frequencies differed from non‐Finnish Europeans, Amish, and Brazilian populations. ABSTRACT The Mennonite population has a unique history of 500 years of genetic isolation shaped by at least three ...
Luiza Beatriz Mayer de Lima   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy