Results 91 to 100 of about 43,790 (245)

Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice

The Anatomical Record, EarlyView.
Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore, Madeline Tourigny, Diana Quinonez, Kevin Barr, Matthew W. Grol, Katherine E. Willmore   +5 more
wiley   +1 more source

Strain uses gap junctions to reverse stimulation of osteoblast proliferation by osteocytes [PDF]

, 2017
Identifying mechanisms by which cells of the osteoblastic lineage communicate in vivo is complicated by the mineralised matrix that encases osteocytes, and thus, vital mechanoadaptive processes used to achieve load‐bearing integrity remain unresolved. We
Aarden, Ajubi, Alford, Bancroft, Batra, Bonewald, Brighton, Bruzzone, Burger, Burger, Burger, Chan, Cheng, Cheng, Cheng, Cheng, Cherian, Cherian, Chiba, Civitelli, Dallas, Damien, Damien, Davidson, Dietrich, Donahue, Doty, Endres, Frost, Genetos, Gluhak-Heinrich, Goldberg, Hasegawa, Heino, Iqbal, Irie, Javaheri, Javaheri, Jiang, Jones, Kamioka, Kato, Kleinnulend, Kulkarni, Lanyon, Nijweide, Osborne, Palumbo, Pitsillides, Rawlinson, Rawlinson, Rawlinson, Rawlinson, Rawlinson, Ren, Schirrmacher, Schwab, Shapiro, Siller-Jackson, Skerry, Skerry, Stanford, Su, Sugawara, Tan, Tanaka, Tanaka-Kamioka, Tatsumi, Taylor, Ulmann, Uzer, Van der Plas, Vazquez, Vezeridis, Weinbaum, Westbroek, Yamaguchi, Yang, Yellowley, You, Zaman, Zaman, Zhao, Ziambaras   +83 more
core   +3 more sources

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Influence of Berberine on Cisplatin Antineoplastic Effect in A549 Cells

Chinese Journal of Lung Cancer, 2015
Background and objective Cisplatin is a standard first-line chemotherapeutic agents for treating advanced non-small cell lung cancer. Unfortunately, the clinical application cisplatin is restricted because it induces serious adverse reaction.
Guojun JIANG, Li LI, Xiaoxiang WU, Shuying DONG, Xuhui TONG   +4 more
doaj   +1 more source

Role of astroglial hemichannels and pannexons in Memory and Neurodegenerative diseases

Frontiers in Integrative Neuroscience, 2016
Under physiological conditions, astroglial hemichannels and pannexin channels allow the release of gliotransmitters from astrocytes. These gliotransmitters are critical in modulating synaptic transmission, plasticity and memory.
Juan Andrés Orellana, Mauricio Antonio Retamal, Rodrigo Moraga Amaro, Jimmy Stehberg   +3 more
doaj   +1 more source

CX43 down-regulation promotes cell aggressiveness and 5-fluorouracil-resistance by attenuating cell stiffness in colorectal carcinoma

Cancer Biology & Therapy, 2023
Chemotherapy is one of the most commonly treatments of advanced colorectal cancer (CRC). However, the drug resistant following chemotherapeutic treatment is a significant challenge in the clinical management of CRC.
Yue Han, Haowei Wang, Hui Chen, Tianyuan Tan, Yiqing Wang, Hongjun Yang, Yanqing Ding, Shuang Wang   +7 more
doaj   +1 more source

Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks [PDF]

, 2018
Collective cell migration mediates multiple tissue morphogenesis processes. Yet how multi-dimensional mesenchymal cell movements are coordinated remains mostly unknown.
Cho, Jung-Hwa, Chow, Robert H., Chuong, Cheng-Ming, He, Lian, Li, Ang, Li, Yuwei, Reid, Brian, Tan, Peng, Tseng, Chun-Chih, Widelitz, Randall B., Wu, Ping, Yeh, Chao-Yuan, Zhao, Min, Zhou, Yubin   +13 more
core   +5 more sources

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Gap junctions in hematopoietic stroma control proliferation and differentiation of blood cell precursors

Anais da Academia Brasileira de Ciências, 2004
We examined gap junction communication in an in vitro model of hematopoiesis, using the murine bone marrow stroma cell line S-17, and primary cultures of murine marrow-derived blood cell precursors.
Bodi Estevão, Hurtado Sandra P., Carvalho Marcelo A., Borojevic Radovan, Carvalho Antônio C. Campos de   +4 more
doaj  

Gap-junctional coupling between neutrophils and endothelial cells [PDF]

, 2003
Communication between leukocytes and endothelial cells is crucial for inflammatory reactions. Paracrine cross-talk and outside-in signaling (via adhesion molecules) have been characterized as communication pathways to date.
Gloe, Torsten, Hoffmann, Anke, Pohl, Ulrich, Zahler, Stefan   +3 more
core   +1 more source