Results 71 to 80 of about 1,371,072 (142)

Expression, purification, and nanodisc reconstitution of connexin-43 hemichannels for structural characterization by cryo-electron microscopyp

open access: yes
Connexins are polytopic domain membrane proteins that form hexameric hemichannels (HCs) which can assemble into gap junction channels (GJCs) at the interface of two neighboring cells. The HCs may be involved in ion and small-molecule transport across the
Lavriha, Pia (author)   +2 more
core   +1 more source

NTPDase2 immunostaining co-localize with connexin 43 in mice bladder.

open access: yes, 2013
Cryosections of mouse bladders were labeled with antibodies to connexin 43 (A. green), NTPDase2 (B. red) and Topro-3 to label nuclei (B. blue). Color merged panels are shown on the right (C). Merged signals of NTPDase2 and connexin 43 are shown as yellow
Weiqun Yu (299931)   +2 more
core   +1 more source

CX43 down-regulation promotes cell aggressiveness and 5-fluorouracil-resistance by attenuating cell stiffness in colorectal carcinoma

open access: yesCancer Biology & Therapy, 2023
Chemotherapy is one of the most commonly treatments of advanced colorectal cancer (CRC). However, the drug resistant following chemotherapeutic treatment is a significant challenge in the clinical management of CRC.
Yue Han   +7 more
doaj   +1 more source

Decreased Expression of Connexin 43 Blunts the Progression of Experimental GN

open access: yes, 2017
International audienceGN refers to a variety of renal pathologies that often progress to ESRD, but the molecular mechanisms underlying this progression remain incompletely characterized.
Labéjof, Lise-Paule   +21 more
core   +1 more source

Embryologisch begründbares Expressionsverhalten von Connexin 43 im Rattenknochen unter Aminobisphosphonatexposition [PDF]

open access: yes, 2022
Summary Background and targets Bisphosphonate associated osteonecrosis of the jaw increasingly occurs spontaneously or as a side-effect following surgical procedures in patients receiving bisphosphonate treatment.
Schiller, Martin
core   +1 more source

Gap junctions in hematopoietic stroma control proliferation and differentiation of blood cell precursors

open access: yesAnais da Academia Brasileira de Ciências, 2004
We examined gap junction communication in an in vitro model of hematopoiesis, using the murine bone marrow stroma cell line S-17, and primary cultures of murine marrow-derived blood cell precursors.
Bodi Estevão   +4 more
doaj  

Photomicrographs depicting fluorescent immunohistochemical staining of connexin-43.

open access: yes, 2013
For fluorescent immunohistochemical analyses, green colour indicates specific immunostaining of connexin-43 and red colour indicates nuclear propidium iodide staining.
Sarwat Sultana (38191)   +7 more
core   +1 more source

Connexin 43 is Involved in Aldosterone-Induced Podocyte Injury

open access: yesCellular Physiology and Biochemistry, 2014
Background/Aims: Connexin43 (Cx43) belongs to a family of transmembrane proteins that build cell-to-cell channels in gap junctions, which play an essential role in intercellular communication, cell proliferation, differentiation and apoptosis. The aim of
Min Yang, Bin Wang, Min Li, Bo Jiang
doaj   +1 more source

Influence of Berberine on Cisplatin Antineoplastic Effect in A549 Cells

open access: yesChinese Journal of Lung Cancer, 2015
Background and objective Cisplatin is a standard first-line chemotherapeutic agents for treating advanced non-small cell lung cancer. Unfortunately, the clinical application cisplatin is restricted because it induces serious adverse reaction.
Guojun JIANG   +4 more
doaj   +1 more source

Antidepressants impact connexin 43 channel functions in astrocytes

open access: yesFrontiers in Cellular Neuroscience, 2016
Glial cells, and in particular astrocytes, are crucial to maintain neuronal microenvironment by regulating energy metabolism, neurotransmitter uptake, gliotransmission and synaptic development.
Tiffany eJeanson   +6 more
doaj   +1 more source

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