Results 51 to 60 of about 1,371,072 (142)

Connexin Expression in Human Minor Salivary Glands: An Immunohistochemical Microscopy Study

open access: yesMolecules, 2022
Connexins (Cxs) are transmembrane proteins involved in the formation of hemichannels and gap junctions (GJs). GJs are involved in various physiological functions, including secretion in glandular tissue. It has been demonstrated that Cx26, Cx32, and Cx43
Alessandra Falleni   +11 more
doaj   +1 more source

The Role of Saturated Fatty Acids in Connexin Expression on Endothelial Cells and Eosinophils [PDF]

open access: yes, 2012
Eotaxin is a potent chemoattractant for eosinophils that becomes elevated in the tissues in response to inflammation and increased adiposity. Therefore, eosinophil migration into adipose tissue should increase in diet-induced obese individuals, yet it ...
Ashack, Kurt Anthony
core  

Effects of Testosterone on the Expression of Connexin 26 and Connexin 43 in the Uterus of Rats During Early Pregnancy [PDF]

open access: yes, 2020
Background/Aim: It was hypothesized that testosterone could affect the distribution and expression of connexin 26 and connexin 43 in the uterus. Thus, the effects of testosterone on these parameters in the uterus during the uterine receptivity period ...
Mohd Helmy Mokhtar   +2 more
core   +1 more source

DEHP alters connexin-43 expression.

open access: yes, 2015
A) Control cardiomyocytes display large plaques of gap junctional connexin-43 (red) on the cellular membranes; DEHP-treated cells have increased intracellular connexin-43 (red). White line denotes the region corresponding to the intensity profiles (right
Hao Ding (186871)   +7 more
core   +1 more source

Connexin 43 contributes to ectopic orofacial pain following inferior alveolar nerve injury

open access: yesMolecular Pain, 2016
Background Clinically, it is well known that injury of mandibular nerve fiber induces persistent ectopic pain which can spread to a wide area of the orofacial region innervated by the uninjured trigeminal nerve branches.
Kaori Kaji DDS   +5 more
doaj   +1 more source

Connexin 43 hemichannels and related diseases

open access: yesAntibody Therapeutics
Abstract Connexin 43 (Cx43) protein forms hemichannels (connexons) and gap junctions, with hemichannels consisting of six Cx43 molecules and gap junctions formed by two hemichannels. While gap junctions are prevalent in organs like the heart and liver, hemichannels are found in specific cell types, such as astrocytes and osteocytes ...
Yanfeng Zhang   +2 more
openaire   +2 more sources

CO2-dependent opening of connexin 43 hemichannels

open access: yeseLife
Sequence and structure comparisons between alpha and beta connexins, Cx43 and Cx26, revealed that Cx43 has a motif, the carbamylation motif, that confers CO2-sensitivity on a subset of beta connexins.
Valentin Mihai Dospinescu   +7 more
doaj   +1 more source

Polymorphism in the C-terminal Cytoplasmic Site, Arginine Phosphorylation Site and 3′UTR of Connexin 43 and its Association with the Progression of Disc Herniation

open access: yesGlobal Spine Journal, 2016
Introduction Intervertebral disc being an avascular tissue, the gap junction protein connexin play an important role in nutrient and extracellular matrix protein play a major role in its structural stability. The pathophysiology underlying the process of
Kavitha Rajsekar   +5 more
doaj   +1 more source

Molecular and functional characterization of gap junctions in the avian inner ear. [PDF]

open access: yes, 2006
To analyze the fundamental role of gap junctions in the vertebrate inner ear, we examined molecular and functional characteristics of gap junctional communication (GJC) in the auditory and vestibular system of the chicken.
Nickel, R, Becker, D, Forge, A
core  

Connexin 43 Upregulation in Mouse Lungs during Ovalbumin-Induced Asthma. [PDF]

open access: yesPLoS ONE, 2015
Connexin (Cx)-based gap junction channels play important roles in the inflammatory response. Cx43 is involved in the pathogenesis of some lung diseases such as acute lung injury. However, the Cx43 expression in asthma is unclear. In the present study, we
Yin Yao   +9 more
doaj   +1 more source

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