Results 31 to 40 of about 23,656 (210)

Connexin43 and Ischemic Preconditioning [PDF]

Cardiovascular Research, 2004
Connexin43 (Cx43) is the essential protein to form hemichannels and gap junctions in the myocardium. The phosphorylation status of Cx43 which is regulated by a variety of protein kinases and phosphatases determines hemichannel and/or gap junction conductance and permeability.
Rainer, Schulz, Gerd, Heusch
openaire   +3 more sources

Expression of Connexin 32 and Connexin 43 in Adenomatous Polyps and Hyperplastic Polyps

Online Türk Sağlık Bilimleri Dergisi, 2021
Objective: Although connexins are thought to provide normally functioning gap junctions via a tumor suppressor gene, new studies point to an abnormal increase of connexins in various carcinomas and sarcomas. Therefore it was aimed to investigate the expression of connexin 43 (Cx43) and connexin 32 (Cx32) in adenomatous and hyperplastic polyps ...
Havva ERDEM, Ali ASLAN, Soner ÇANKAYA, Zeynep DOĞANGÜZEL   +3 more
openaire   +4 more sources

Connexin 43 Affects Osteogenic Differentiation of the Posterior Longitudinal Ligament Cells via Regulation of ERK Activity by Stabilizing Runx2 in Ossification

Cellular Physiology and Biochemistry, 2016
Aims: Connexin 43 is one of the most potent gap junction proteins related to osteoblast differentiation and bone formation. We hypothesized that Connexin 43 is a significant factor in osteogenic differentiation in the posterior longitudinal ligament ...
Haisong Yang, Lei Shi, Guodong Shi, Yongfei Guo, Dechun Chen, Deyu Chen, Jiangang Shi   +6 more
doaj   +1 more source

IMMUNOHISTOCHEMICAL LOCALIZATION OF CONNEXIN 43 IN THE CORNEA OF THE ONE HUMPED CAMEL (CAMELUS DROMEDARIES) [PDF]

Assiut Veterinary Medical Journal, 2015
The present study has described for the first time the expression of connexin 43 in the cornea of camel. The camel cornea was composed of five layers, the corneal epithelium, subepithelial basement membrane (Bowman’s membrane), substantiapropria or ...
ENAS A.A. ELHAFEZ, KHALED ALY
doaj   +1 more source

Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro

BMC Cardiovascular Disorders, 2006
Background Organ transplantation is presently often the only available option to repair a damaged heart. As heart donors are scarce, engineering of cardiac grafts from autologous skeletal myoblasts is a promising novel therapeutic strategy.
Kienast Yvonne, Ullrich Nina D, MacLeod Kenneth T, Spohr Hilmar, Patel Pravina, Themis Michael, Ma Yu-Ling, Tolmachov Oleg, Coutelle Charles, Peters Nicholas S   +9 more
doaj   +1 more source

The Importance of Connexin 43 in Enamel Development and Mineralization [PDF]

Frontiers in Physiology, 2018
During enamel development, formation of hydroxyapatite crystals and regulation of pH in the enamel matrix require massive transport of ions. Both ameloblasts and adjacent dental epithelial cells in the stellate reticulum co-express several transmembrane cotransporters/ion-exchangers for transport of ions across plasma membranes.
Sali Al-Ansari, Rozita Jalali, Lilian I. Plotkin, Lilian I. Plotkin, Lilian I. Plotkin, Antonius L. J. J. Bronckers, Pamela DenBesten, Yan Zhang, Judith E. Raber-Durlacher, Judith E. Raber-Durlacher, Jan de Lange, Frederik R. Rozema, Frederik R. Rozema   +12 more
openaire   +7 more sources

Gating and regulation of connexin 43 (Cx43) hemichannels [PDF]

Proceedings of the National Academy of Sciences, 2003
Connexin 43 (Cx43) nonjunctional or “unapposed” hemichannels can open under physiological or pathological conditions. We characterize hemichannels comprised of Cx43 or Cx43-EGFP (Cx43 with enhanced GFP fused to the C terminus) expressed in HeLa cells. Channel opening was induced at potentials greater than +60 mV.
Contreras, JE, Sáez, JC, Bukauskas, FF, Bennett, MVL   +3 more
openaire   +5 more sources

Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue

Reproductive Biology and Endocrinology, 2006
Background Prolonged labour is associated with greater morbidity and mortality for mother and child. Connexin 43 is a major myometrial gap junction protein found in human myometrium.
Malmström Anders, Cebers Gvido, Dahlqvist Camilla, Klimaviciute Aurelija, Byström Birgitta, Cluff Ann, Ekman-Ordeberg Gunvor   +6 more
doaj   +1 more source

Immunohistochemistry using an antibody to unphosphorylated connexin 43 to identify human myometrial interstitial cells

Reproductive Biology and Endocrinology, 2008
Background Myometrial smooth myocytes contract as a result of electrical signalling via a process called excitation-contraction coupling. This process is understood in great detail at the cellular level but the generation and coordination of electrical ...
Van Lommel Alfons, Roskams Tania, Deprest Jan, Gevaert Thomas, Hutchings Graham, Nilius Bernd, De Ridder Dirk   +6 more
doaj   +1 more source

Connexin 43: Key roles in the skin

Biomedical Reports, 2017
Gap junctions are tightly packed intercellular channels that serve a common purpose of allowing the intercellular exchange of small metabolites, second messengers and electrical signals. Connexins (Cxs) are gap junction proteins. Currently, 20 and 21 members of Cxs have been characterized in mice and humans, respectively. Connexin 43 (Cx43) is the most
Xiao-Fei, Zhang, Xiaofeng, Cui
openaire   +3 more sources