Results 31 to 40 of about 1,371,072 (142)
Connexin 43: An Interface Connecting Neuroinflammation to Depression
Molecules, 2023 Major depressive disorder (MDD) is a leading chronic mental illness worldwide, characterized by anhedonia, pessimism and even suicidal thoughts. Connexin 43 (Cx43), mainly distributed in astrocytes of the brain, is by far the most widely and ubiquitously
Hong Jiang +3 more
doaj +1 more source
Journal of Experimental & Clinical Cancer Research, 2010 Background bFGF is an important growth factor for glioma cell proliferation and invasion, while connexin 43 is implicated in the suppression of glioma growth.
Liu Hongsheng +5 more
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Connexin43 and Ischemic Preconditioning [PDF]
Cardiovascular Research, 2004 Connexin43 (Cx43) is the essential protein to form hemichannels and gap junctions in the myocardium. The phosphorylation status of Cx43 which is regulated by a variety of protein kinases and phosphatases determines hemichannel and/or gap junction conductance and permeability.
Rainer, Schulz, Gerd, Heusch
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Visfatin reduces gap junction mediated cell-to-cell communication in proximal tubule-derived epithelial cells [PDF]
, 2013 Background/Aims: In the current study we examined if the adipocytokine, visfatin, alters connexinmediated intercellular communication in proximal tubule-derived epithelial cells.
Mark J. Wall +7 more
core +1 more source
Cellular Physiology and Biochemistry, 2016 Aims: Connexin 43 is one of the most potent gap junction proteins related to osteoblast differentiation and bone formation. We hypothesized that Connexin 43 is a significant factor in osteogenic differentiation in the posterior longitudinal ligament ...
Haisong Yang +6 more
doaj +1 more source
IMMUNOHISTOCHEMICAL LOCALIZATION OF CONNEXIN 43 IN THE CORNEA OF THE ONE HUMPED CAMEL (CAMELUS DROMEDARIES) [PDF]
Assiut Veterinary Medical Journal, 2015 The present study has described for the first time the expression of connexin 43 in the cornea of camel. The camel cornea was composed of five layers, the corneal epithelium, subepithelial basement membrane (Bowman’s membrane), substantiapropria or ...
ENAS A.A. ELHAFEZ, KHALED ALY
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Expression of Connexin 32 and Connexin 43 in Adenomatous Polyps and Hyperplastic Polyps
Online Türk Sağlık Bilimleri Dergisi, 2021 Objective: Although connexins are thought to provide normally functioning gap junctions via a tumor suppressor gene, new studies point to an abnormal increase of connexins in various carcinomas and sarcomas. Therefore it was aimed to investigate the expression of connexin 43 (Cx43) and connexin 32 (Cx32) in adenomatous and hyperplastic polyps ...
Havva ERDEM +3 more
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BMC Cardiovascular Disorders, 2006 Background Organ transplantation is presently often the only available option to repair a damaged heart. As heart donors are scarce, engineering of cardiac grafts from autologous skeletal myoblasts is a promising novel therapeutic strategy.
Kienast Yvonne +9 more
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Gating and regulation of connexin 43 (Cx43) hemichannels [PDF]
Proceedings of the National Academy of Sciences, 2003 Connexin 43 (Cx43) nonjunctional or “unapposed” hemichannels can open under physiological or pathological conditions. We characterize hemichannels comprised of Cx43 or Cx43-EGFP (Cx43 with enhanced GFP fused to the C terminus) expressed in HeLa cells. Channel opening was induced at potentials greater than +60 mV.
Contreras, JE +3 more
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The Importance of Connexin 43 in Enamel Development and Mineralization [PDF]
Frontiers in Physiology, 2018 During enamel development, formation of hydroxyapatite crystals and regulation of pH in the enamel matrix require massive transport of ions. Both ameloblasts and adjacent dental epithelial cells in the stellate reticulum co-express several transmembrane cotransporters/ion-exchangers for transport of ions across plasma membranes.
Sali Al-Ansari +12 more
openaire +7 more sources