Results 31 to 40 of about 43,790 (245)

Dynamic changes in connexin expression correlate with key events in the wound healing process. [PDF]

, 2003
Wound healing is a complex process requiring communication for the precise co-ordination of different cell types. The role of extracellular communication through growth factors in the wound healing process has been extensively documented, but the role of
Becker, David L, Coutinho, Petula, Frank, Stefanie, Qiu, Cindy, Tamber, Kamaldeep   +4 more
core   +1 more source

Astroglial connexin 43 sustains glutamatergic synaptic efficacy [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2014
Astrocytes dynamic interactions with neurons play an active role in neurotransmission. The gap junction (GJ) subunits connexins 43 and 30 are strongly expressed in astrocytes and have recently been shown to regulate synaptic activity and plasticity.
Chever, Oana, Pannasch, Ulrike, Ezan, Pascal, Rouach, Nathalie   +3 more
openaire   +4 more sources

Connexin-43-dependent ATP release mediates macrophage activation during sepsis

eLife, 2019
Bacterial spillage into a sterile environment following intestinal hollow-organ perforation leads to peritonitis and fulminant sepsis. Outcome of sepsis critically depends on macrophage activation by extracellular ATP-release and associated autocrine ...
Michel Dosch, Joël Zindel, Fadi Jebbawi, Nicolas Melin, Daniel Sanchez-Taltavull, Deborah Stroka, Daniel Candinas, Guido Beldi   +7 more
doaj   +1 more source

Connexin 43 plays a role in pulmonary vascular reactivity in mice [PDF]

, 2018
Pulmonary arterial hypertension (PAH) is a chronic condition characterized by vascular remodeling and increased vaso-reactivity. PAH is more common in females than in males (~3:1).
Andrew Shaw, Bradley Foote, Ergul, Jane Nally, Johnstone, MacLean, Myo Htet, Patricia Martin, Van Kempen, Yang, Yang, Yvonne Dempsie   +11 more
core   +1 more source

Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endothelium

BMC Medicine, 2008
Background The modulation of gap junctional communication between tumor cells and between tumor and vascular endothelial cells during tumorigenesis and metastasis is complex.
Gillespie Mark N, Dobrowolski Radoslaw, Willecke Klaus, Haroon Abu, Elzarrad M Khair, Al-Mehdi Abu-Bakr   +5 more
doaj   +1 more source

Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. [PDF]

, 2020
Male factor infertility is a problem in today's society but many underlying causes are still unknown. The generation of a conditional Sertoli cell (SC)-specific connexin 43 (Cx43) knockout mouse line (SCCx43KO) has provided a translational model ...
Behr, Rüdiger, Brehm, Ralph HJ, Distl, Ottmar, Hilbold, Erika, Hoedemaker, Martina, Jung, Klaus, Langeheine, Marion, Metzger, Julia, Rajkovic, Aleksandar, Rode, Kristina, Wilkening, Sandra   +10 more
core   +1 more source

Adenovirus-mediated delivery of bFGF small interfering RNA increases levels of connexin 43 in the glioma cell line, U251

Journal of Experimental & Clinical Cancer Research, 2010
Background bFGF is an important growth factor for glioma cell proliferation and invasion, while connexin 43 is implicated in the suppression of glioma growth.
Liu Hongsheng, Xu Xinnu, Wang Jinhuan, Feng Xuequan, Zhang Biao, Lin Na   +5 more
doaj   +1 more source

An overview of the focus of the International Gap Junction Conference 2017 and Future Perspectives [PDF]

, 2018
n/
Kwak, Brenda R., Martin, Patricia E.
core   +2 more sources

Connexin 43 Affects Osteogenic Differentiation of the Posterior Longitudinal Ligament Cells via Regulation of ERK Activity by Stabilizing Runx2 in Ossification

Cellular Physiology and Biochemistry, 2016
Aims: Connexin 43 is one of the most potent gap junction proteins related to osteoblast differentiation and bone formation. We hypothesized that Connexin 43 is a significant factor in osteogenic differentiation in the posterior longitudinal ligament ...
Haisong Yang, Lei Shi, Guodong Shi, Yongfei Guo, Dechun Chen, Deyu Chen, Jiangang Shi   +6 more
doaj   +1 more source

Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro

BMC Cardiovascular Disorders, 2006
Background Organ transplantation is presently often the only available option to repair a damaged heart. As heart donors are scarce, engineering of cardiac grafts from autologous skeletal myoblasts is a promising novel therapeutic strategy.
Kienast Yvonne, Ullrich Nina D, MacLeod Kenneth T, Spohr Hilmar, Patel Pravina, Themis Michael, Ma Yu-Ling, Tolmachov Oleg, Coutelle Charles, Peters Nicholas S   +9 more
doaj   +1 more source