Results 11 to 20 of about 43,790 (245)
Antidepressants impact connexin 43 channel functions in astrocytes [PDF]
Frontiers in Cellular Neuroscience, 2016 Glial cells, and in particular astrocytes, are crucial to maintain neuronal microenvironment by regulating energy metabolism, neurotransmitter uptake, gliotransmission and synaptic development.
Tiffany eJeanson +6 more
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Connexin 43: An Interface Connecting Neuroinflammation to Depression
Molecules, 2023 Major depressive disorder (MDD) is a leading chronic mental illness worldwide, characterized by anhedonia, pessimism and even suicidal thoughts. Connexin 43 (Cx43), mainly distributed in astrocytes of the brain, is by far the most widely and ubiquitously
Hong Jiang +3 more
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Expression and function of Connexin 43 and Connexin 37 in the murine zona glomerulosa [PDF]
Physiological ReportsThe zona glomerulosa (ZG) synthesizes the mineralocorticoid aldosterone. The primary role of aldosterone is the maintenance of volume and electrolyte homeostasis.
Gabriel Stölting +6 more
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Fluoxetin Upregulates Connexin 43 Expression in Astrocyte
Basic and Clinical Neuroscience, 2014 Introduction: Recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (MS).
Hossein Mostafavi +8 more
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Role of gap junctions and connexin 43 in cancerogenesis and tumor metastasis [PDF]
Medicinski Podmladak, 2022 Gap junctions are intercellular connections that enable direct communication between neighboring cells. They are important in tissue homeostasis, cell growth, and differentiation.
Savić Ivana +2 more
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Function of Connexin-43 in Macrophages [PDF]
International Journal of Molecular Sciences, 2020 Recent studies have helped to increase the understanding of the function of Connexin-43 (Cx43) in macrophages (Mφ). The various roles of Cx43 in Mφs range from migration, antigen-presentation and some forms of intercellular communication to more delicate processes, such as electrochemical support in the propagation of the heartbeat, immunomodulatory ...
Daniel Rodjakovic +2 more
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Connexin 43 signalling and cardioprotection [PDF]
Heart, 2005 Connexin (Cx) 43 is the predominant protein forming gap junctions and non-junctional hemichannels in ventricular myocardium. The Cx43 proteins are central to the cardioprotection afforded by ischaemic preconditioning (IP). The specific role of mitochondrial C×43 in protection by IP is reviewed.
K, Boengler, R, Schulz, G, Heusch
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Connexin 26 and Connexin 43 in Canine Mammary Carcinoma [PDF]
Veterinary Sciences, 2019 Incidence of canine mammary carcinoma is two times higher than the rate of human breast cancer. Mammary tumors are the most common type of cancer in intact female dogs and account for about half of all neoplasms in these dogs. Well-established models of breast cancer have shown that neoplastic cells often have a loss of intercellular communication ...
Savannah Luu +3 more
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Enhanced osteoclastic resorption and responsiveness to mechanical load in gap junction deficient bone. [PDF]
PLoS ONE, 2011 Emerging evidence suggests that connexin mediated gap junctional intercellular communication contributes to many aspects of bone biology including bone development, maintenance of bone homeostasis and responsiveness of bone cells to diverse extracellular
Yue Zhang +8 more
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Identification of Connexin-43 Interacting Proteins [PDF]
Cell Communication & Adhesion, 2003 Connexin-43 (Cx43), the most ubiquitously expressed vertebrate gap junction protein, has been shown to interact directly with Zonula Occludens-1 (ZO-1). Although several potential functions have been proposed for the ZO-1/Cx43 interaction, the role that ZO-1 and other Cx43-interacting partners play in the regulation of Cx43 trafficking, assembly ...
Deepika, Singh, Paul D, Lampe
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