Results 11 to 20 of about 23,656 (210)
The Role of Connexin 43 in Lung Disease [PDF]
Life, 2020 The term lung disease describes a broad category of disorders that impair lung function. More than 35 million Americans have a preventable chronic lung disease with high mortality rates due to limited treatment efficacy.
Julie A. Swartzendruber +2 more
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Connexin 43 Controls the Astrocyte Immunoregulatory Phenotype [PDF]
Brain Sciences, 2018 Astrocytes are the most abundant glial cells of the central nervous system and have recently been recognized as crucial in the regulation of brain immunity.
Anne-Cécile Boulay +8 more
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Connexin 43 impacts on mitochondrial potassium uptake [PDF]
Frontiers in Pharmacology, 2013 In cardiomyocytes, connexin 43 (Cx43) forms gap junctions and unopposed hemichannels at the plasma membrane, but the protein is also present at the inner membrane of subsarcolemmal mitochondria.
Kerstin eBoengler +4 more
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Fluoxetin Upregulates Connexin 43 Expression in Astrocyte
Basic and Clinical Neuroscience, 2014 Introduction: Recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (MS).
Hossein Mostafavi +8 more
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Function of Connexin-43 in Macrophages [PDF]
International Journal of Molecular Sciences, 2020 Recent studies have helped to increase the understanding of the function of Connexin-43 (Cx43) in macrophages (Mφ). The various roles of Cx43 in Mφs range from migration, antigen-presentation and some forms of intercellular communication to more delicate processes, such as electrochemical support in the propagation of the heartbeat, immunomodulatory ...
Daniel Rodjakovic +2 more
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Connexin 43 signalling and cardioprotection [PDF]
Heart, 2005 Connexin (Cx) 43 is the predominant protein forming gap junctions and non-junctional hemichannels in ventricular myocardium. The Cx43 proteins are central to the cardioprotection afforded by ischaemic preconditioning (IP). The specific role of mitochondrial C×43 in protection by IP is reviewed.
K, Boengler, R, Schulz, G, Heusch
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Connexin 26 and Connexin 43 in Canine Mammary Carcinoma [PDF]
Veterinary Sciences, 2019 Incidence of canine mammary carcinoma is two times higher than the rate of human breast cancer. Mammary tumors are the most common type of cancer in intact female dogs and account for about half of all neoplasms in these dogs. Well-established models of breast cancer have shown that neoplastic cells often have a loss of intercellular communication ...
Savannah Luu +3 more
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Postępy Higieny i Medycyny Doświadczalnej, 2020 Skeleton formation and its proper functioning is possible thanks to specialized bone tissue cells: bone forming osteoblasts, bone resorbing osteoclasts and osteocytes located in bone cavities. Gap junctions are transmembrane channels connecting neighboring cell. Thanks to gap junctions it is possible for signals to be directly transmitted by cells. Gap
Krzysztof Łukowicz +3 more
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Identification of Connexin-43 Interacting Proteins [PDF]
Cell Communication & Adhesion, 2003 Connexin-43 (Cx43), the most ubiquitously expressed vertebrate gap junction protein, has been shown to interact directly with Zonula Occludens-1 (ZO-1). Although several potential functions have been proposed for the ZO-1/Cx43 interaction, the role that ZO-1 and other Cx43-interacting partners play in the regulation of Cx43 trafficking, assembly ...
Deepika, Singh, Paul D, Lampe
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Expression of connexin-43 in surgical resections of primary tumor and lymph node metastases of squamous cell carcinoma and adenocarcinoma of the lung: a retrospective study [PDF]
PeerJ, 2022 Background Connexins are transmembrane proteins forming gap junctions between the cells, which allow intercellular communication. Significance of gap junctions and connexins in lung carcinoma is not yet understood.
Ivana Savic +4 more
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