Results 81 to 90 of about 1,371,072 (142)
The role of connexin 43 in mediating odor response
Connexin proteins are the hemichannels that form gap junctions to regulate the intercellular communication. Connexin 43 (Cx43) is the most common gap junction protein that expresses in many cell types, including the olfactory sensory neurons. Phosphorylation is a crucial step to regulate the function of Cx43. Gap junction was found to modulate the odor
Yiqun, Yu, Chunbo, Zhang
openaire +2 more sources
Connexin 43 and hearing: Possible implications for retrocochlear auditory processing
OBJECTIVES/HYPOTHESIS: To examine the relationship between hearing and connexin 43, a dominant gap junctional protein in the central nervous system. STUDY DESIGN: Original research. METHODS: Connexin 43 heterozygous mice are used to assess its mutational
Edmund Nahm +9 more
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Low dose ionizing radiation-induced activation of connexin 43 expression
Purpose: Connexin 43 has been implicated in the cellular response to ionizing radiation by enabling cell-to-cell communication. It is established here that the expression of connexin 43 is affected by ionizing radiation and the mechanism involved is ...
Little, JB (15560072) +3 more
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Role of astroglial hemichannels and pannexons in Memory and Neurodegenerative diseases
Under physiological conditions, astroglial hemichannels and pannexin channels allow the release of gliotransmitters from astrocytes. These gliotransmitters are critical in modulating synaptic transmission, plasticity and memory.
Juan Andrés Orellana +3 more
doaj +1 more source
Nonlinear behaviour of conduction and block in cardiac tissue with heterogeneous expression of connexin 43 [PDF]
Altered gap junctional coupling potentiates slow conduction and arrhythmias. To better understand how heterogeneous connexin expression affects conduction at the cellular scale, we investigated conduction in tissue consisting of two cardiomyocyte ...
Prudat, Yann, Kucera, Jan
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Connexin 43 phosphorylation and degradation are required for adipogenesis
Connexin-43 (Cx43) is a membrane phosphoprotein that mediates direct inter-cellular communication by forming gap junctions. In this way Cx43 can influence gene expression, differentiation and growth. Its role in adipogenesis, however, is poorly understood.
Yeganeh, Azadeh +5 more
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Connexin-43 (Cx43) channels do not mediate the mean event probability.
(A) Localization of Cx43 (white in the Cx43 only image, yellow in the composite image). Cells were counter-stained with rhodamine phalloidin (red) and DAPI (blue).
Sung Jun Son (6631073) +8 more
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Effects of Connexin 43 Inhibition in an Ovalbumin-induced Mouse Model of Asthma
Connexion 43 (Cx43), a gap junction protein, is expressed abundantly in the airway and has been implicated in the pathogenesis of asthma. However, the effects of blocking Cx43 in asthma remain unclear.
Jian-Qiang Huang +5 more
doaj
Plant extracts are rich in various bioactive compounds, such as polyphenols, flavonoids, tannins, terpenoids, phenolic acids, saponins, alkaloids, and polysaccharides.
Gintarė Jančiukė +4 more
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CONNEXIN 43 HEMICHANNELS CAN DRIVE THE GLIOBLASTOMA SPREADING
Glioblastoma (GBM) is the most common and aggressive primary tumor of the central nervous system (CNS) among high-grade gliomas (HGG). Patients with GBM often have a poor prognosis.
doaj +1 more source

