Results 111 to 120 of about 38,372 (307)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

POWER OF THE WEAKNESS OF A LITERARY CHARACTER AS AFFIRMATION OF THE AUTHOR'S SEMANTIC SYSTEM [PDF]

open access: yesHum, 2019
The success of the characterization of urban female characters in Bozic's Kurlani novels was touched upon only incidentally for the purpose of interpreting other structural elements of the novel or Bozic's poetics, and these characters were referred to ...
Mirela Šušić
doaj  

La connotation, par C. Kerbrat-Orecchioni

open access: yes, 1980
Gandon Francis. La connotation, par C. Kerbrat-Orecchioni. In: Communication et langages, n°47, 3ème-4ème trimestre 1980. pp.
Gandon, Francis-Marie
core  

DENOTATION AND CONNOTATION ON ‘PATHETIC FAIRY TALE BY SAPTARASA

open access: yes, 2019
Lyrics of songs are almost similar to poetry, which distinguishes them from song lyrics that do not require deep diction to refer to majas or symbols. Therefore, many song lyrics revolve around the meaning of denotations and connotations.
Sutikno, Eka Ugi
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Bacon on metal, situations, objects, and architectural connotation

open access: yes, 1997
An architecture must be developed that understands its inherent capabilities and limitations to communicate to its public audience through architectural connotation--architecture that is conscious of its implicit meaning--such is the goal of this thesis.
Troppmann, Joseph Anthony
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Autonymie et connotation autonymique dans le Bourgeois gentilhomme de Molière

open access: yes, 2000
Peifer Michel. Autonymie et connotation autonymique dans le Bourgeois gentilhomme de Molière. In: L'Information Grammaticale, N. 85, 2000. pp.
Peifer, Michel
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Typeface Connotation

open access: yes, 2015
Since the invention of movable type, letters and characters of the Western alphabet have worn many different typefaces. The same way clothing can suggest fragments of the persona of who wears them, it has been suggested that typefaces carry connotative ...
Ferrari, Matias   +1 more
core  

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