Results 111 to 120 of about 358,200 (372)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Türkiye Selçuklu Sultanı I. İzzeddîn Keykâvus'un Antalya’yı Fethi ve Fetihnâmeleri

open access: yesOrtaçağ Araştırmaları Dergisi
Oldukça köklü bir tarihi geçmişe sahip olan Antalya şehri, Antikçağ ve Ortaçağ boyunca Anadolu'nun en önemli Akdeniz liman kentlerinden olmuş ve farklı milletlerden birçok hükümdarın egemenliği altına girmiştir.
Mahmut Demir
doaj   +1 more source

Critique [of Economic and Psychic Exploitation of American Indians] [PDF]

open access: yes, 1983
James Joyce once said that history is a nightmare from which I am trying to awake. This article by Gretchen Bataille and Charles Silet is part of our collective process of awakening.
Simmons, Terry
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Geography, Geopolitics, and International Law. Atlantic Expansion in the Late Middle Ages

open access: yesRevista Atlántida
Este artículo examina la política atlántica ibérica durante los siglos xv y xvi a través de la lente de la geopolítica, teniendo en cuenta al mismo tiempo el espacio geográfico y la imaginación espacial.
Julia Bühner
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

The Physcomitrella Genome Reveals Evolutionary Insights into the Conquest of Land by Plants

open access: yesScience, 2008
S. Rensing   +69 more
semanticscholar   +1 more source

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