Results 121 to 130 of about 314,852 (352)
Journal on European History of LawThere are some provisions on the vassal’s obligation to respond to the king’s call to arms in the 13th century Hungarian legislation. In this paper we aim to compare the Hungarian legislation with the European ius commune on this subject, and we try to ...
Péter Bónis
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Evolution and Revolution: The Drama of Realtime Complementarity [PDF]
, 1972 This article is by design a response to Alastair M. Taylor's "For Philosophers and Scientists: A General Systems Paradigm." That work is an advance over stage theories. But its focus on modernization tacitly accepts marginalization.
Byrne, Edmund
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Malinche and the Conquest of Mexico. An Attempt at Historical Reconstruction
Ибероамериканские тетрадиThe author sets forward a hypothesis of his own (though based on reliable sources) of the course of events that led to the subdual or, more exactly, to the loss of power of the Aztec Empire over what is now Mexico and the fall of the land under control ...
A. V. Sadikov
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Historic Conditions of Mongolia’s Loss of Independence in 17-18th Сenturies
Oriental Studies, 2018 The article focuses on studying the Mongol-Manchu’s struggle which resulted in loss of independence of Mongols. There are some main factors in the process of the conquest of Mongolia. The first one is political and feudal disruption of Mongols. Since the
G. Khishigjargal
doaj
The Mongols’ Baghdad: Knowledge Transmission through Manuscript Cultures before and after the Conquest – Introduction [PDF]
Bruno De Nicola, Nadine Löhr
openalex +1 more source