Results 111 to 120 of about 314,852 (352)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Türkiye Selçuklu Sultanı I. İzzeddîn Keykâvus'un Antalya’yı Fethi ve Fetihnâmeleri
Ortaçağ Araştırmaları DergisiOldukça köklü bir tarihi geçmişe sahip olan Antalya şehri, Antikçağ ve Ortaçağ boyunca Anadolu'nun en önemli Akdeniz liman kentlerinden olmuş ve farklı milletlerden birçok hükümdarın egemenliği altına girmiştir.
Mahmut Demir
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Locating Religion, Controlling Territory: Conquest and Legitimation in Late Ninth-Century Vaspurakan and its Interreligious Context [PDF]
, 2016 Zaroui Pogossian
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
‘Enacted in the destiny of sedentary peoples’: racism, discovery and the grounds of law [PDF]
, 2000 Whilst the racial, and racist, basis of the doctrine of discovery is a modern innovation, the doctrine owes much to its pre-modern forms and ethos. The finding and settlement of putatively unknown lands has long been attended with mythic and religious ...
Fitzpatrick, Peter
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Universal Alliance of All Peoples : Romantic Socialists, the Human Family, and the Defense of Empire during the July Monarchy, 1830-1848 [PDF]
, 2011 This article documents the procolonial rhetoric among romantic socialists in France during the July Monarchy (1830-48), demonstrating its pervasiveness.
Andrews, Naomi J.
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source