Results 131 to 140 of about 69,612 (292)

CONQUEST-ADVANCE: Achieving proDuctiVe implementAtioN of CONQUEST Quality Standards in COPD Care. [PDF]

Pragmat Obs Res
Vijaykumar E, Gatenby J, Evans A, Henley W, Eleangovan N, Couper A, Kerr M, Ariti C, Busby J, Alves L, Bafadhel M, Bhutani M, Carter V, Chen R, Chalmers J, Crooks MG, Devereux G, Dickens AP, Freeman D, Gale CP, Gibson JM, Halpin D, Hickman K, Hurst JR, Marshall J, Martinez FJ, Miravitlles M, Mullerova H, Morris T, Muro S, Natman J, Quint JK, Sharma A, Singh D, Singh M, Stolz D, Pullen R, Varghese D, Wilkinson TM, Winders T, Price D.   +40 more
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

23 AHI does not adequately reflect OSA severity

BMJ Open Respiratory Research, 2021
Emma Lombard, Simon Merritt
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Intravascular Plaque Modification With Rotational Atherectomy Technique for Recanalization of Heavily Calcified Chronic Total Occlusion. [PDF]

JACC Case Rep
Qin Q, Zhou Y, Xu R, Wu M, Ding Z, Ma J, Ge J.   +6 more
europepmc   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Retention Royale: a Gamified Territory-Conquest Add-on for Anki to Enhance Engagement with Spaced Repetition. [PDF]

Med Sci Educ
Whitford T, Goldberg C, Hussain SS, Etienne M.   +3 more
europepmc   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Stefan Rinke, Conquistadoren und Azteken. Cortés und die Eroberung Mexikos

Nuevo mundo - Mundos Nuevos, 2023
Daniel Rojas
doaj   +1 more source

Balloon tamponade for central venous catheter-related perforations: A minimally invasive, vessel-sparing case series. [PDF]

JTCVS Struct Endovasc
Jalili J, Vaseghi S, Baastani Khajeh M.
europepmc   +1 more source