Results 151 to 160 of about 295,617 (280)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Intra-Calcium Modification: New Promise for Calcified Nodule in Percutaneous Coronary Intervention? [PDF]

JACC Case Rep
Leung C, Chan AKC.
europepmc   +1 more source

Conquest and Violence: The Christian critique of Muhammad [PDF]

, 2014
Grafton, David D.
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Granular cell tumour of the breast: A rare mimic of breast carcinoma. [PDF]

Ultrasound
Taylor J, Ali ZAS, Shah E, Howlett D.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Marina Zuloaga Rada, La conquista negociada: guarangas, autoridades locales e imperio en Huaylas, Perú (1532-1610), Lima, IEP-IFEA, 2012, 316 p.

Nuevo mundo - Mundos Nuevos, 2014
Silvia Escanilla Huerta
doaj   +1 more source

Self-completed patient-reported outcome measures in adults with epilepsy: A review. [PDF]

Epilepsia Open
Conquest AL, O'Brien TJ, Kwan P, French JA, Malpas CB, Foster EC.   +5 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Gregorio Salinero, La trahison de Cortés. Désobéissances, procès politiques et gouvernement des Indes de Castille, seconde moitié du XVIe siècle

Nuevo mundo - Mundos Nuevos, 2017
Aude Argouse
doaj   +1 more source