Results 51 to 60 of about 295,617 (280)

Contemporary Evidence, Treatment Strategies, and Indications for Chronic Total Occlusion-Percutaneous Coronary Intervention

open access: yesEuropean Medical Journal, 2017
Chronic total occlusions (CTOs) are detected incidentally in ˜20% of patients undergoing coronary angiography and are often associated with significant morbidity and mortality. CTOs can manifest with worsening symptoms, reduced left ventricular function,
Deshan Weeraman   +2 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Introduction [PDF]

open access: yes, 1998
The costs and benefits of European Imperialism from the conquest of Ceuta, 1415, to the Treaty of Lusaka, 1974.Twelfth International Economic History Congress. Madrid, 1998.Patrick K.
O'Brien, Patrick K.   +1 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Predatory Value: Economies of Dispossession and Disturbed Relationalities [PDF]

open access: yes, 2018
This essay introduces and theorizes the central concerns of this special issue, “Economies of Dispossession: Indigeneity, Race, Capitalism.” Financialization, debt, and the accelerated concentration of wealth today work through social relations already ...
Byrd, Jodi A.   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Византийцы на Боспоре VI в. / The Byzantines on Bosporus at 6th century CE

open access: yesМатериалы по археологии и истории античного и средневекового Крыма, 2017
The article examines the history of the Byzantine conquest of the Cimmerian Bosporus in the 6th century CE. through the prism of the prosopographical approach.
Bolgov N.N.
doaj   +1 more source

Premières représentations du Huyapari (alias Orénoque) (1498-1552) : la quête de Meta et ses revers

open access: yesNuevo mundo - Mundos Nuevos, 2020
The great American rivers have been more obstacles than channels of communication for the Spanish or Portuguese conquerors. Their gigantism and the Amazonian natural environment with regard to the Amazon and the Orinoco, provoked a scrambled geographical
Louise Bénat-Tachot
doaj   +1 more source

Ariel - Volume 2 Number 1 [PDF]

open access: yes, 1969
Editors Delvun C. Case, Jr. Paul M. Fernhoff Associate Editors Donald Bergman Daniel B. Gould Richard Bonanno Ronald Hoffman Lay-Out Editor Carol Dolinskas Sports Editor James Nocon Business Manager Nick Grego Contributing Editors Michael J.
Bergman, Donald   +7 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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