Results 81 to 90 of about 69,612 (292)
, 2005 Born in England, John Conquest followed the piper to Austin and launched his journal Music City Texas in 1989 to document the burgeoning live performance industry—especially the alt-country and singer-songwriter genres.
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, 2006 Born in England, John Conquest followed the piper to Austin and launched his journal Music City Texas in 1989 to document the burgeoning live performance industry—especially the alt-country and singer-songwriter genres.
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Les crises aux Etats-Unis depuis 1837 : facteurs de renouveau et de redéploiement
IdeAs, 2013 Crises in the US since the first half of the nineteenth century have often been more brutal than elsewhere, but have also been pregnant with more tangible changes and irrational promises. These would-be apocalypses, although unwittingly fertile, are also
Jean Luc Tendil
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RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
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Türkiye Selçuklu Sultanı I. İzzeddîn Keykâvus'un Antalya’yı Fethi ve Fetihnâmeleri
Ortaçağ Araştırmaları DergisiOldukça köklü bir tarihi geçmişe sahip olan Antalya şehri, Antikçağ ve Ortaçağ boyunca Anadolu'nun en önemli Akdeniz liman kentlerinden olmuş ve farklı milletlerden birçok hükümdarın egemenliği altına girmiştir.
Mahmut Demir
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Continuidades históricas en la conquista de América [PDF]
Revista Colombiana de Ciencias Sociales, 2016 El trabajo busca proporcionar una imagen de síntesis del proceso de la conquista de América. Se destaca el enorme cambio cultural generado desde la conquista, como las tendencias de continuidad del proceso histórico en mención.
Felipe Cárdenas Tamara
doaj
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source