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Proteins are characterized by their structures and functions, and these two fundamental aspects of proteins are assumed to be related. To model such a relationship, a single representation to model both protein structure and function would be convenient,
Fernando Fontove, Gabriel Del Rio
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Increased Utilization of Storm Surge Barriers: A Research Agenda on Estuary Impacts
Rising coastal flood risk and recent disasters are driving interest in the construction of gated storm surge barriers worldwide, with current studies recommending barriers for at least 11 estuaries in the United States alone.
Philip Orton+8 more
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Background Phosphine (PH3) resistance in stored grain insect pests poses a significant challenge to effective pest control strategies worldwide. This study delved into understanding PH3-resistant mechanism, with the objective of informing robust and ...
Donghyeon Kim+3 more
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Metropolitan smart growth centers: An assessment of incentive policies in four regions
Across the United States, metropolitan areas face challenges related to transportation and land use. An emerging policy in many regions is to promote development around higher-density, mixed-use (smart-growth) centers that create locally accessible nodes;
Richard D Margerum+3 more
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CONCERNING NEW STANDARDS OF TREATMENT OF THE PERIPHERAL ARTERIES DISEASES ON BACKGROUND OF MODERN RECOMMENDATIONS AND DATA OF CLINICAL INVESTIGATIONS, TAKING INTO ACCOUNT A SIGNIFICANCE OF PROPHYLAXIS OF UNFAVORABLE EVENTS WITH THE EXTREMITY AND CARDIO ...
CONSENSUS OF EXPERTS
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Sarcopenia: revised European consensus on definition and diagnosis
Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia.
A. Cruz-Jentoft+28 more
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MAFLD: A consensus-driven proposed nomenclature for metabolic associated fatty liver disease.
Fatty liver associated with metabolic dysfunction is common, affects a quarter of the population, and has no approved drug therapy. While pharmacotherapies are in development, response rates appear modest.
M. Eslam, A. Sanyal, J. George
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Innovation from a Memetic and Evolutionary Perspective
Innovation happens all around the Universe and is a fundamental mechanism of evolution. Living creatures cannot but exist and develop through innovation. Innovation happens through mutations that make sense in retrospect only.
Andrej Drapal
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The Consensus Molecular Subtypes of Colorectal Cancer
Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and drug responses. To resolve inconsistencies among the reported gene expression–based CRC classifications and facilitate clinical translation, we formed an international
J. Guinney+39 more
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Disclaimer: These ACMG Standards and Guidelines were developed primarily as an educational resource for clinical laboratory geneticists to help them provide quality clinical laboratory services.
Sue Richards+11 more
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