Results 141 to 150 of about 249,976 (301)

Erdos: A Novel Blockchain Consensus Algorithm with Equitable Node Selection and Deterministic Block Finalization [PDF]

The introduction of blockchain technology has brought about significant transformation in the realm of digital transactions, providing a secure and transparent platform for peer-to-peer interactions that cannot be tampered with.
Jianming Yong, Sello, Buti, Yong, Jianming, Tao, Xiaohui, Xiaohui Tao, Buti Sello   +5 more
core   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source

Implementation of Procalcitonin in Antibiotic Stewardship: Derivation of a Consensus Algorithm for Procalcitonin Use in Clinical Practice. [PDF]

Infect Chemother, 2022
Park DW, Choi JY, Kim CJ, Kim JH, Kim HB, Lee DG.   +5 more
europepmc   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Improved Method of Blockchain Cross-Chain Consensus Algorithm Based on Weighted PBFT. [PDF]

Comput Intell Neurosci, 2022
Lei L, Song L, Wan J.
europepmc   +1 more source

Consensus Algorithms for Trees and Strings. [PDF]

, 2003
This thesis studies the computational complexity and polynomial-time approximability of a number of discrete combinatorial optimization problems involving labeled trees and strings. The problems considered have applications to computational molecular biology, pattern matching, and many other areas of computer science.
openaire   +1 more source

Simulation and Analysis of Bitcoin Consensus Algorithm

, 2018
Bitcoin is one of the earliest and most popular applications in the blockchain. It does not need a trusted third-party organizations to trade more efficiently. Bitcoin nodes form a peer-to-peer distributed network to transfer blocks.
Shih, Yun-Rou
core  

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Quantum blockchain based on asymmetric quantum encryption and a stake vote consensus algorithm. [PDF]

Sci Rep, 2022
Wang W, Yu Y, Du L.
europepmc   +1 more source

Correctness proof for the majority consensus algorithm

, 1986
We give a formal proof of correctness of the Thomas majority consensus algorithm using temporal ...
Ravichandran, A., Shyamasundar, R. K.
core   +1 more source