Advanced Science, EarlyView.This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Application of International Society for the Study of Women's Sexual Health consensus algorithm for persistent genital arousal disorder/genito-pelvic dysesthesia to 10 cases and use of epidural spinal injections as long term management. [PDF]
Sex MedAhrendt H +4 more
europepmc +1 more source
Sparc: a sparsity-based consensus algorithm for long erroneous sequencing reads. [PDF]
PeerJ, 2016 Ye C, Ma ZS.
europepmc +1 more source
Amortized Averaging Algorithms for Approximate Consensus [PDF]
, 2015 Bernadette Charron-Bost +2 more
openalex +1 more source
Advanced Science, EarlyView.SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He +5 more
wiley +1 more source
Advanced Science, EarlyView.We analyzed long‐read genomic sequencing data obtained from 40 inbred mouse strains to produce a large database of structural variants. This dataset captures the major types of structural variants, which includes deletions, insertions, duplications, and inversions.
Wenlong Ren +6 more
wiley +1 more source
Reduction and prevention of agitation in persons with neurocognitive disorders: an international psychogeriatric association consensus algorithm. [PDF]
Int PsychogeriatrCummings J +15 more
europepmc +1 more source
Additive and Partially Dominant Effects from Genomic Variation Contribute to Rice Heterosis
Advanced Science, EarlyView.Additive and partially dominant effects, namely at mid‐parent levels or values between mid‐parent and parental levels, respectively, are the predominant inheritance patterns of heterosis‐associated molecules. These two genetic effects contribute to heterosis of agronomic traits in both rice and maize, as well as biomass heterosis in Arabidopsis ...
Zhiwu Dan +8 more
wiley +1 more source
Generalized Distributed Consensus-based Algorithms for Uncertain Systems and Networks
, 2010 Ion Matei
openalex +1 more source
LO042: Sonography in Hypotension and Cardiac Arrest (SHoC) - Hypotension: derivation of an evidence-based consensus algorithm for the integration of point of care ultrasound into resuscitation of hypotensive patients [PDF]
, 2016 Paul Atkinson +32 more
openalex +1 more source