Results 201 to 210 of about 3,095,141 (299)

Cross‐scale Material‐Structure Synergy for 2D Metamaterials: Toward Customizable Intelligent Electromagnetic Manipulation in Multiphysics Fields

open access: yesAdvanced Science, EarlyView.
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang   +5 more
wiley   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

open access: yesAdvanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang   +11 more
wiley   +1 more source

Palaeoproteomic Deconvolution of Physical and Genetic Collagen Mixtures

open access: yesAdvanced Science, EarlyView.
ClassiCOL_v2 uses a novel “peptide patching” framework that treats any collagen sample as a patchwork of peptide sequences derived from phylogenetically related species. This allows the algorithm to simultaneously resolve two previously intractable problems: multi‐species samples and/or database deficiencies.
Ian Engels   +12 more
wiley   +1 more source

Granzyme B PET Imaging Reveals Lgmn+ Macrophage‐Mediated Immune Evasion and Guides Immunotherapy in EGFR‐TKI‐Resistant NSCLC

open access: yesAdvanced Science, EarlyView.
Graphical illustration of 68Ga‐GZB PET/CT imaging reveals immune dynamics post‐EGFR‐TKI resistance in NSCLC; Lgmn+ macrophages‐derived Lgmn‐containing extracellular vesicles inhibit glycolysis, induce CD8+ T cell exhaustion, and targeting Lgmn restores immunotherapy sensitivity.
Dongliang Wang   +9 more
wiley   +1 more source

Reduction and prevention of agitation in persons with neurocognitive disorders: an international psychogeriatric association consensus algorithm. [PDF]

open access: yesInt Psychogeriatr
Cummings J   +15 more
europepmc   +1 more source

Anode‐Free Sodium Metal Batteries: From Materials Design to System‐Level Integration

open access: yesAdvanced Science, EarlyView.
Anode‐free sodium metal batteries hold no sodium reserve, so every inefficiency becomes permanent loss. Resolving the inventory into reversible, dead, and chemically bound fractions exposes what Coulombic efficiency hides. Practical 500‐cycle operation requires above 99.95%, a threshold few systems meet under lean electrolyte and high areal capacity ...
Hamid Hussain   +10 more
wiley   +1 more source

Salvianolic Acid a Disrupts the HSP90α‐AKT‐PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells

open access: yesAdvanced Science, EarlyView.
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan   +8 more
wiley   +1 more source

On the consensus algorithm of IPChain

open access: yes, 2019
A consensus algorithm is the core of a blockchain, a technology that allows the development of flexible trust relationships in distributed systems. This project aims to design and develop a consensus algorithm for IPchain, a blockchain that will act as a security layer for the inter-domain routin.
openaire   +1 more source

Home - About - Disclaimer - Privacy