Results 41 to 50 of about 6,083,657 (309)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Oregon Recycling Steering Committee process report

, 2020
prepared by: Oregon Consensus, National Policy Consensus Center, Portland State University.Title from PDF cover (viewed on November 4, 2020)."This report is respectfully submitted to DEQ by the Oregon Consensus Facilitation Team to conclude the Recycling

core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Group Formation Tracking Control for Air–Ground Multi-Agent Systems

Guidance, Navigation and Control
This paper presents a weight-based group formation tracking control method for air–ground multi-agent systems, where the system consists of unmanned aerial vehicles (UAVs) and unmanned ground vehicles (UGVs).
Haichao Liu, Juntong Qi, Yan Peng, Yuan Ping, Chong Wu, Mingming Wang, Hailong Huang   +6 more
doaj   +1 more source

Consensus control of discrete-time heterogeneous multi-agent systems

工程科学学报, 2016
Consensus problems were investigated for discrete-time heterogeneous multi-agent systems composed of first-order agents and second-order agents. Distributed consensus protocols with and without the bound communication delay were respectively designed. By
LIU Cong, ZHOU Qiang, HU Xiao-guang
doaj   +1 more source

Possibilities of Consensus: Toward Democratic Moral Discourse

, 1991
The concept of consensus is often appealed to in discussions of biomedical ethics and applied ethics, and it plays an important role in many influential ethical theories.
Jennings, Bruce
core   +1 more source

International eDelphi Study to Reach Consensus on the Methotrexate Dosing Regimen in Patients With Psoriasis.

, 2022
A clear dosing regimen for methotrexate in psoriasis is lacking, and this might lead to a suboptimal treatment. Because methotrexate is affordable and globally available, a uniform dosing regimen could potentially optimize the treatment of patients with ...
Gyulai, R., Torres, T., Valenzuela, F., Iversen, L., Gulliver, W., Gomez, L.C., Oon, H.H., Claréus, B.W., Kolalapudi, S.A., da Cruz Costa, S.A., Menting, S.P., de la Cruz, C., Llamas-Velasco, M., Gómez-Flores, M., Zheng, M., Schejtman, A.A., de Souza Sittart, J.A., Damiani, G., Cetkovska, P., Csányi, I., Oakley, A., Gebauer, K.A., Velásquez-Lopera, M.M., Gooderham, M.J., Del-Río, R., Carretero, G., Goujon, C., Franco, M.D., Handjani, F., Romiti, R., Griffiths, CEM, Luna, P.C., Firooz, A., le Cleach, L., Félix, PAO, Fábos, B., Spuls, P.I., Misery, L., Ramam, M., de Jong, EMGJ, Castro-Ayarza, J.R., Akman-Karakas, A., Hsiao, J.P., Maldonado-García, C., Salleras I Redonnet, M., García-Doval, I., Ferran, M., van der Kraaij, G.E., Schram, M.E., Choon, S.E., Ferrándiz, C., Chosidow, O., Vestergaard, C., Ayanlowo, O., Jullien, D., Correa, C.C., Nicolopoulos, J., Willaert, F., Törocsik, D., Mälkönen, T., Liu, T.Y., Yawalkar, N., Middelkamp-Hup, M.A., Ramos, AMC, Sator, P., Novoa, F.D., Brajac, I., El Gamal, E., de la Cueva, P., Varela, P., Trcko, K., Araujo, R.R., Babic, L.T., Chandrashekar, L., Lafuente-Urrez, R.F., Drvar, D.L., Abad, M.E., van den Reek, JMPA, Grewal, P., de Oliveira, MFSP, Reich, K., Fernandez-Peñas, P., Ceovic, R., Sonkoly, E., Gonzalez, C., Carija, A., Cárdenas Rojas, P.J., Prinz, J.C., Barber, K., Vílchez-Márquez, F., Janmohamed, S.R., Skov, L., Weightman, W., Hurtová, T., Kumar, A.S., Veldkamp, W., Echeverría, C.M., Weinberg, J.M., Ingram, J.R., Doss, N., Fardet, L., Polic, M.V., Egeberg, A., Marchesi, C., Azimi, S.Z., Colombo, E.P., Zargari, O., Horváth, B., Sharma, V.K., Balak, D., Muresanu, L.I., van Huizen, A.M., Dutil, M., Kaštelan, M., Hong, C.H., Mahil, S.K., Gonçalo, M., Bylaite-Bucinskiene, M., Krnjevic-Pezic, G., Wells, J., Gulin, S.J., Krisztián, G., Turchin, I., de Rie, M.A., Lecluse, L., Lebwohl, M., Warren, R.B., Sikora, M., Reciné, T.R., Foulkes, A., Riad, H., Huldt-Nystrøm, T., Castro, C., Hunter, HJA, Ghislain, P.D., Seyger, MMB, Silverberg, N.B., Danespazhooh, M., Rademaker, M., Vender, R., Kim, D.H., Sanchez, J.L., Leonidze, T., Kui, R., Puig, L., Laffitte, E., Olszewska, M., Grozdev, I., Frez, M.L., Moussa, I.O., Lambert, JLW, El-Sayed, M.H., Margasin, S.M., Mahé, E., Khobzei, K., Massari, L.P., Marrón, S.E., Fougerousse, A.C., Wiseman, M.C., van Doorn, M., Handa, S., Vilarrasa, E., Gonzalez, G.O., Maul, L.V., Calzavara-Pinton, P., Wong, T.W., Matlock, B.H., Maul, J.T., Appelen, D., Boonen, HPJ, Conrad, C., Pellerano, G., Gisondi, P., Holló, P., Urbancek, S.   +174 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Fixed‐time stability of stochastic nonlinear systems and its application into stochastic multi‐agent systems

IET Control Theory & Applications, 2021
The paper devotes to study fixed‐time stability of stochastic nonlinear systems and fixed‐time consensus of stochastic multi‐agent systems (SMASs). Firstly, a new fixed‐time stability theorem is established and a high‐precise estimation of settling time ...
Jiaju Yu, Shuanghe Yu, Yan Yan
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source