Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Developmental Timing and Network Directionality in the Triple-Network Model of Anorexia Nervosa. [PDF]
Hagan KE.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Comparison of event-specific drinking motives reported at the first drink versus retrospectively the next morning. [PDF]
Boyle HK +5 more
europepmc +1 more source
A Model for Comprehensive Material Degradation and Strength Characteristics Assessment of Historic Masonry Structures. [PDF]
Miedziałowski C +2 more
europepmc +1 more source
Accounting for Comorbidity in Etiologic Research. [PDF]
Khachadourian V, Janecka M.
europepmc +1 more source
The Knudsen Layer in the Heat Transport Beyond the Fourier Law: Application to the Wave Propagation at Nanoscale. [PDF]
Carlomagno I, Sellitto A.
europepmc +1 more source
Suicidality as a potential risk and therapeutic target during widespread GLP-1 receptor agonists use: implications of inflammation. [PDF]
Borovcanin MM, Petrovic I.
europepmc +1 more source
Varifold solutions to volume-preserving mean curvature flow: existence and weak-strong uniqueness. [PDF]
Poiatti A.
europepmc +1 more source

