Results 61 to 70 of about 967,378 (249)
Microclimate Management for the Preservation of Cultural Heritage
This paper presents a line of research aimed at studying in detail the interaction between air conditioning/heating systems and thermo hygrometric conditions inside museums.
Salvatore Alterio +4 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Art and environment as media for ecosustainability, ethics and aesthetics
“Art, both in a strict sense, but also in a broader sense, that is to say environmental and cultural heritage – considering, as it correctly should be, the environment with its individual compartments of air, soil and water – is indissolubly linked to ...
Salvatore Lorusso, Angela Braida
doaj +1 more source
Conservation implications of the refugee species concept and the European bison: king of the forest or refugee in a marginal habitat? [PDF]
Graham I. H. Kerley +2 more
openalex +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
A note from the restoration world: the Raffaello completed?
History of a restoration work that had opened the way to a new, fascinating attribution hypothesis for a drawing that was considered a Giulio Romano’s work and today it is considered a Raffaello’s work, with a subsequently partial intervention of his ...
Pietro Livi
doaj +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Chemistry: our Life, our Future
In this note we look at a number of aspects relating to chemistry that have had a strong impact on the future of humanity. In particular, some technological innovations have been examined which have had a strong impact on daily life in general; the role ...
Ferruccio Trifirò
doaj +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source

