Results 61 to 70 of about 1,779,244 (346)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

The Honoris Causa Degree in Conservazione dei Beni Culturali to Friedrich Krinzinger. Considerations on the conservation on the spot of excavation finds

Conservation Science in Cultural Heritage, 2004
Friedrich Krinzinger, Professor of Classic Archaeology at the Vienna University and director of the Austrian Archaeological Institute has been interested in the techniques and in their applications in archaeology since he was young and he funded and ran ...
Eugenio Russo
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Il progetto di ricerca BLU-ARCHEOSYS: tecnologie innovative e sistemi avanzati di supporto per l’archeologia subacquea

Conservation Science in Cultural Heritage, 2014
In this article we summarize the main findings of the research project, BLU- ARCHEOSYS. It ranges from results achieved in the support systems of the human operations carried out directly in the underwater world, such as vision systems for 3D ...
Lucio Colizzi
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

From the history of the recognitions of the remains to the reconstruction of the face of Dante Alighieri by means of techniques of virtual reality and forensic anthropology

Conservation Science in Cultural Heritage, 2007
The work consists of the reconstruction of the face of the great poet called Dante Alighieri through a multidisciplinary approach that matches traditional techniques (manual ones), usually used in forensic anthropology, with digital methodologies that ...
Stefano Benazzi, Giorgio Gruppioni, Massimliano Fantini, Francesca De Crescenzio, Franco Persiani, Francesco Mallegni, Gabriele Mallegni   +6 more
doaj   +1 more source

Truly Conserving with Conservative Remapping Methods

Geoscientific Model Development, 2023
Abstract. Conservative mapping of data from one horizontal grid to another should preserve certain integral or mean properties of the original data. This may be essential in some model applications, including ensuring realistic exchange of energy and mass between coupled model components.
openaire   +3 more sources

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Michelangelo Buonarroti: Restoration of the Frescoes on the Vaulted Ceiling and the Last Judgment in the Sistine Chapel

Conservation Science in Cultural Heritage, 2017
The last restoration of Michelangelo’s frescoes in the Sistine Chapel was directed and conducted by the internal staff of the Vatican Museums, in the period from June 1980 to April 1994.
Gianluigi Colalucci
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source