Results 111 to 120 of about 22,400 (311)

Seed rain and soil seed banks limit native regeneration within urban forest restoration plantings in Hamilton City, New Zealand

, 2012
Restoration of native forest vegetation in urban environments may be limited due to isolation from native seed sources and to the prevalence of exotic plant species.
Overdyck, Elizabeth, Clarkson, Bruce D.
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Restoration of three indigenous forest types in Tauranga City, New Zealand

, 2013
This research examined the current state and developmental trajectory of forest restoration projects in Tauranga City with the aim of establishing whether they will eventually develop into functioning forest ecosystems similar to their natural ...
Dean, Hamish Alston
core  

Conservation of saproxylic species [PDF]

, 2010
Forest management has altered the prerequisite of many species in forest landscapes. The new, more conservation-oriented forest management includes a range of different strategies that aim to prevent losses of biodiversity. Evaluating these strategies is
Djupström, Line
core  

Altitude-adaptive water use strategies of grassland are constrained by air dryness and stoichiometry in southwest of China

Frontiers in Plant Science
IntroductionUnderstanding the elevational patterns of intrinsic water-use efficiency (iWUE) and their drivers is crucial for predicting plant adaptation and ecosystem responses to climate change. However, how iWUE in different photosynthetic pathways (C3
Jiankun Bai, Jiankun Bai, Deping Zhai, Deping Zhai, Yang Xu, Yang Xu, Deyun Chen, Deyun Chen, Wei Wang, Wei Wang, Ziyue Xu, Ziyue Xu, Yuhui Si, Yuhui Si, Fujia Yang, Fujia Yang, Mei Sun, Mei Sun, Yinfeng Zhang, Yinfeng Zhang, Zhigang Chen, Zhigang Chen, Juan Yang, Juan Yang, Wenhui Cui, Wenhui Cui, Junbao Yu, Junbao Yu, Xiaoli Cheng, Xiaoli Cheng   +29 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Decline and restoration ecology of Australian seagrasses

, 2018
Irving, A ORCiD: 0000-0002-9763-2148; Jackson, EL ORCiD: 0000-0003-1708-4776Since the first version of this book almost 30 years ago, significant losses of seagrass meadows have continued to be reported from around Australia as a result of natural and ...
Statton, J, Orth, RJ, RJ Orth (9886856), Emma Jackson (9806846), GA Kendrick (9886838), Kendrick, GA, Dixon, KW, Jackson, EL, J Statton (9886850), Irving, AD, EA Sinclair (9886859), Sinclair, EA, KW Dixon (9886853), Andrew Irving (9806627)   +13 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source