Results 91 to 100 of about 179,947 (308)
LandEcological security patterns (ESPs) are fundamental to safeguarding regional ecological integrity and enhancing human well-being. Consequently, research on conservation and restoration in critical regions is vital for ensuring ecological security and optimizing territorial ecological spatial configurations.
Shuaiqi Chen, Zhengzhou Ji, Longhui Lu
openaire +2 more sources
Plantation forests and biodiversity conservation [PDF]
, 2003 There are five key reasons why biodiversity conservation should be considered a part of plantation management. (1) The plantation estate is large, and balancing various land management values with wood and pulp production is important when extensive ...
Hobbs, R.J., Lindenmayer, D.B., Salt, D.
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Are current ecological restoration practices capturing natural levels of genetic diversity? A New Zealand case study using AFLP and ISSR data from mahoe (Melicytus ramiflorus) [PDF]
, 2015 Sourcing plant species of local provenance (eco-sourcing) has become standard practice in plant community restoration projects. Along with established ecological restoration practices, knowledge of genetic variation in existing and restored forest ...
Clarke, Andrew C. +4 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Once and Future Gulf of Mexico Ecosystem: Restoration Recommendations of an Expert Working Group [PDF]
, 2011 The Deepwater Horizon (DWH) well blowout released more petroleum hydrocarbons into the marine environment than any previous U.S. oil spill (4.9 million barrels), fouling marine life, damaging deep sea and shoreline habitats and causing closures of ...
Charles H. Peterson +17 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The third dimension in landscape metrics analysis applied to Central Alentejo-Portugal [PDF]
, 2010 Landscape metrics have been widely developed over the last two decades, although the question remains: How does landscape metrics relates with ecological processes?
Batista, Teresa +2 more
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Guangxi ZhiwuEffects of different nitrogen fertilizer application rates on fruit quality of pitaya under the condition of calcareous soil in karst area were discussed in order to investigate the effects of nitrogen fertilizer application level on fruit quality of ...
CHEN Ting +5 more
doaj +1 more source