Results 41 to 50 of about 381,080 (315)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Bear conservation genetics [PDF]

open access: yesNature, 1992
Times Cited: 42 ; International ...
Taberlet, P., Bouvet, J.
openaire   +2 more sources

Using eDNA for mammal inventories still needs naturalist expertise, a meta‐analysis

open access: yesEcology and Evolution, 2023
DNA from the environment (eDNA) has been increasingly used as a new tool to conduct biodiversity assessment. Because of its noninvasive and less time‐consuming nature, many studies of recent years solely rely on this information to establish a species ...
Pauline Van Leeuwen, Johan Michaux
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Fragmentation genetics in the tropics [PDF]

open access: yes, 2018
On the 23rd of February, some 50 Conservation Geneticists from around the global gathered for a half day symposium entitled ‘Fragmentation Genetics in the Tropics' held at the Friedrich-Alexander University, Erlangen, Germany as part of the German ...
Finger, Aline, Kettle, Chris
core  

Population Genetics of Rare Variants and Complex Diseases [PDF]

open access: yes, 2012
Identifying drivers of complex traits from the noisy signals of genetic variation obtained from high throughput genome sequencing technologies is a central challenge faced by human geneticists today.
Hernandez, Ryan D.   +3 more
core   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Microsatellite loci development and population genetics in Neotropical fish Curimata mivartii (Characiformes: Curimatidae) [PDF]

open access: yesPeerJ, 2018
The Curimatidae family plays an ecological role in the recycling and distribution of nutrients and constitutes a major food source for several commercially important fishes.
Ricardo M. Landínez-García   +1 more
doaj   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

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