Results 41 to 50 of about 381,080 (315)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Bear conservation genetics [PDF]
Times Cited: 42 ; International ...
Taberlet, P., Bouvet, J.
openaire +2 more sources
Using eDNA for mammal inventories still needs naturalist expertise, a meta‐analysis
DNA from the environment (eDNA) has been increasingly used as a new tool to conduct biodiversity assessment. Because of its noninvasive and less time‐consuming nature, many studies of recent years solely rely on this information to establish a species ...
Pauline Van Leeuwen, Johan Michaux
doaj +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Fragmentation genetics in the tropics [PDF]
On the 23rd of February, some 50 Conservation Geneticists from around the global gathered for a half day symposium entitled ‘Fragmentation Genetics in the Tropics' held at the Friedrich-Alexander University, Erlangen, Germany as part of the German ...
Finger, Aline, Kettle, Chris
core
Population Genetics of Rare Variants and Complex Diseases [PDF]
Identifying drivers of complex traits from the noisy signals of genetic variation obtained from high throughput genome sequencing technologies is a central challenge faced by human geneticists today.
Hernandez, Ryan D. +3 more
core +2 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Microsatellite loci development and population genetics in Neotropical fish Curimata mivartii (Characiformes: Curimatidae) [PDF]
The Curimatidae family plays an ecological role in the recycling and distribution of nutrients and constitutes a major food source for several commercially important fishes.
Ricardo M. Landínez-García +1 more
doaj +2 more sources
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source

