Results 161 to 170 of about 1,527,554 (269)

Conservation genomics reveals pesticide and pathogen exposure in the declining bumble bee Bombus terricola. [PDF]

Mol Ecol, 2021
Tsvetkov N, MacPhail VJ, Colla SR, Zayed A.   +3 more
europepmc   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Conservation Genomics of <i>Apocynum venetum</i>: Genetic Adaptation and Demographic History Across China's Saline-Alkali Ecosystems. [PDF]

Evol Appl
Yuan N, Jia C, Lu R, Yuan X, Chen X.
europepmc   +1 more source

The First Genome of the Balearic Shearwater (Puffinus mauretanicus) Provides a Valuable Resource for Conservation Genomics and Sheds Light on Adaptation to a Pelagic lifestyle. [PDF]

Genome Biol Evol, 2022
Cuevas-Caballé C, Ferrer Obiol J, Vizueta J, Genovart M, Gonzalez-Solís J, Riutort M, Rozas J.   +6 more
europepmc   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Conservation genomics of two endangered buntings reveal genetic diversity before and after severe population declines. [PDF]

BMC Biol
Wang S, Zhang D, Jiao X, Wu L, Zhu QH, Lv H, Wang H, Han Z, Li S, He P, Chen J, Feng S, Olsson U, Alström P, Lei F.   +14 more
europepmc   +1 more source

Expanding the conservation genomics toolbox: Incorporating structural variants to enhance genomic studies for species of conservation concern. [PDF]

Mol Ecol, 2021
Wold J, Koepfli KP, Galla SJ, Eccles D, Hogg CJ, Le Lec MF, Guhlin J, Santure AW, Steeves TE.   +8 more
europepmc   +1 more source

The BTB/POZ‐MATH Protein ZmBPM1 Interacts With Autophagy‐related Protein ZmATG6 and Modulates the NLR Protein Rp1‐D21‐Mediated Defense Response in Maize

Advanced Science, EarlyView.
The maize BTB/POZ‐MATH (BPM) protein ZmBPM1 interacts with autophagy‐related protein ZmATG6 to relocate the NLR protein Rp1‐D21 from the nucleo‐cytoplasmic compartment into autophagosome‐like puncta, leading to autophagy‐mediated turnover and suppressing the hypersensitive response.
Chang‐Xiao Tang, Tong‐Tong Liu, Qi‐Dong Ge, Xiao‐Ying Liu, Wanxiao Wang, Yang Sun, Yanfei Liu, Faqiang Li, Guan‐Feng Wang   +8 more
wiley   +1 more source

Complete chloroplast genome of <i>Euphorbia resinifera</i>: overcoming biogeographical bias in phylogenetic inference and establishing a conservation genomics framework for threatened North-West African cactiform species. [PDF]

Front Plant Sci
Taha A, Rabeh K, Lamara M, Gaboun F, Laadsi I, Lebkiri N, Diria G, Abdelwahd R, Saghir K, Ettaqy A, El-Mderssa M, Khamar H, Johnson MG, Fokar M, Abbas Y.   +14 more
europepmc   +1 more source

Conservation genomics of sibling grouse in boreal forests reveals introgression and adaptive population differentiation in genes controlling epigenetic variation. [PDF]

Zool Res, 2022
Song K, Gao B, Halvarsson P, Fang Y, Klaus S, Jiang YX, Swenson JE, Han ZM, Sun YH, Höglund J.   +9 more
europepmc   +1 more source