Results 191 to 200 of about 200,820 (302)

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

Orchid bee diversity responds positively to forest cover and landscape heterogeneity in the Brazilian Savanna. [PDF]

Oecologia
de Sousa FG, Bergamini LL, Diniz MF, De M Júnior P, Collevatti RG, Silva DP.   +5 more
europepmc   +1 more source

Field‐Frustrated Cooperative Distortions: Suppressing Jahn‐Teller Ordering via Microwave Annealing

Advanced Science, EarlyView.
Microwave annealing decouples local Jahn‐Teller distortions from long‐range cooperative ordering in CuFe2O4, stabilizing a metastable cubic phase that remains locally distorted yet globally symmetry‐frustrated. Synchrotron XRD, PDF, XPS, and in situ thermal cycling reveal how non‐equilibrium MW‐phonon interactions suppress cooperative orbital‐lattice ...
Daryoosh Vashaee, Kelvin Dsouza
wiley   +1 more source

Advancing national strategies for the conservation of Indonesia’s threatened plants and wildlife

Oryx
Ahmad Munawir, Oki Hidayat, Nuril Fadzilah, Misbah Satria Giri, Yogi Prasetio   +4 more
doaj   +1 more source

Water Level Regulation Regime Shifts Drive Divergent Foraging Habitat Use by Wintering Hooded Cranes (<i>Grus monacha</i>) in Shallow Gate-controlled Lakes of the Yangtze Floodplain. [PDF]

Ecol Evol
Fang Y, Zhong Y, Zhou L, Liang M.
europepmc   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Based on "space-culture-role" three-dimensional integration perspective for construction of characteristic conservation areas for traditional villages in Southwest Zhejiang, China. [PDF]

Sci Rep
Zhao X, Tao J, Liu F.
europepmc   +1 more source

Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor

Advanced Science, EarlyView.
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao, Dongdong Liu, Haishan Gao, Chenyang Qin, Wen Zhang, Ziyun Lu, Dongxia Tan, Yuxiu Qu, Yusong Liu, Zhiran Zou, Hongtao Yu, Wei Qi   +11 more
wiley   +1 more source

Conservation Practices for Protecting and Enhancing Soil and Water Resources in Growing and Changing Communities [PDF]

, 2008
Association of Illinois Soil and Water Conservation Districts, Natural Resources Conservation Service   +1 more
core   +1 more source

Social capital and its influence on sustainable economic development and natural resource management among ethnic minorities in Phu Tho province, Vietnam. [PDF]

PLoS One
Vu VK, Vu KH, Vu TTN.
europepmc   +1 more source