Results 131 to 140 of about 62,065 (264)

Distance-Limited Larval Replenishment in the Deep-Sea Mussel Gigantidas platifrons Challenges Connectivity-Based Conservation Planning. [PDF]

Mol Ecol
Zhong Z, Zhou L, Chen H, Cai C, Yan Y, Ye Z, Li M, Wang J, Zhang H, Wang H, Cao L, Sun Y, Lian C, Guo Y, Feng J, Wang M, Li C.   +16 more
europepmc   +1 more source

China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications

Advanced Science, EarlyView.
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu, Zhiyu Tian, Zhengxian Zhang, Xinbei Li   +3 more
wiley   +1 more source

Occurrence data for habitat suitability modelling to support conservation planning in Latvia: species list, observations and ecogeographical variable selection. [PDF]

Biodivers Data J
Starka R, Rūsiņa S, Auniņa L, Balalaikins M, Butkeviča J, Cera I, Čakstiņa D, Čeirāns A, Gailis J, Liepiņa L, Leimanis I, Mežaka A, Moisejevs R, Ozols J, Pilāte D, Priedniece I, Riters R, Rubene B, Strazdiņa L, Šakele V, Vancāns A, Vērpēja V, Vintulis V, Župerka MA, Vinogradovs I, Auniņš A, Avotiņš A.   +26 more
europepmc   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Lessons learned using species' distribution models for conservation planning in the Golden Gate Biosphere reserve. [PDF]

PLoS One
Syphard AD, Rustigian-Romsos H, Franco D, Forrestel A.   +3 more
europepmc   +1 more source

Narrowly distributed taxa are disproportionately informative for conservation planning. [PDF]

Sci Rep, 2022
Akasaka M, Kadoya T, Fujita T, Fuller RA.   +3 more
europepmc   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

Hong Kong orchids on the EDGE: a phylogenetic framework for conservation planning, trade mitigation and population rescue. [PDF]

Front Plant Sci
Li J, Zhang J, Gale SW.
europepmc   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Conservation Planning and Reporting Implications of qPCR-based Multi-species eDNA Detection Under EU Environmental Regulations. [PDF]

Environ Manage
Giovacchini S, Mirone E, Bruno A, Ramazzotti F, Caprotti L, Monaco P, Di Febbraro M, Manfrin C, Jamwal PS, Belluardo F, Galimberti A, Loy A.   +11 more
europepmc   +1 more source