Results 151 to 160 of about 765,552 (311)

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Conservation plan [PDF]

Nature, 1988
openaire   +1 more source

Current practices in marine systematic conservation planning: protocol for a global scoping review. [PDF]

Open Res Eur, 2023
Fabbrizzi E, Giakoumi S, Petza D, Katsanevakis S, Domínguez Crisóstomo E, Colloca F, Elliot M, Flannery W, Galparsoro I, Kruse M, Ben Lamine E, McAteer B, Stelzenmüller V, Fraschetti S.   +13 more
europepmc   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Spatiotemporal dynamics of complex ecological networks: Power-law scaling and implications for conservation planning [PDF]

, 2008
Spatial constraints on the topology of complex networks are just beginning to be appreciated, both theoretically and in concrete examples like the Internet and global air transportation network.
Christopher Wright
core   +2 more sources

Koala Genome Survey: An Open Data Resource to Improve Conservation Planning. [PDF]

Genes (Basel), 2023
Hogg CJ, Silver L, McLennan EA, Belov K.
europepmc   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Saving our species [PDF]

Science is vital to our conservation management. Our ecologists work hand-in-hand with land managers to plan and deliver effective conservation management for Australia’s species.
Jim Radford
core  

Mapping suitable habitats for globally endangered raptors in Kenya: Integrating climate factors and conservation planning. [PDF]

Ecol Evol, 2023
Ngila PM, Chiawo DO, Owuor MA, Wasonga VO, Mugo JW.   +4 more
europepmc   +1 more source

Interfacial Engineering by Metallic Ions and Organic Ammonium Ligand Passivation for Perovskite Solar Cells

Advanced Science, EarlyView.
A synergistic approach using phenethylammonium iodide (PEAI) and antimony iodide (SbI3) enhances the operational stabilities of perovskite solar cells by providing p‐type doping effect, suitable band energy alignment, reduced defect density, and minimized surface ion vacancies in the perovskite films.
Abraham Adenle, Purevlkham Myagmarsereejid, Selengesuren Suragtkhuu, Tuul Tsagaantsooj, Solongo Purevdorj, Eric Campbell, Sina Jamali, Oisín E. FitzGerald, Taylor J. Z. Stock, Thomas J. Macdonald, Joseph F. S. Fernando, Hui Jin, Paul E. Shaw, Michitoshi Hayashi, Batjargal Sainbileg, Chihaya Adachi, Yu Lin Zhong, Munkhbayar Batmunkh   +17 more
wiley   +1 more source