In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Integrating conservation costs into sea level rise adaptive conservation prioritization
Biodiversity conservation requires strategic investment as resources for conservation are often limited. As sea level rises, it is important and necessary to consider both sea level rise and costs in conservation decision making.
Mingjian Zhu +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Comparison of growth, photosynthetic, and chlorophyll fluorescence characteristics of different native cultivars in Castanea henryi [PDF]
[Objective] The production of Castanea henryi is a new industry in Guizhou province of China. Many native cultivars have been introduced from Fujian province in resent years. Their adaptability remains unclear.
XU Bin +6 more
doaj +1 more source
Freshwater wetlands play an important role in preserving global biodiversity and substantial ecosystem services, but they are exposed to higher pressures and threats and have received less attention in conservation planning in comparison to terrestrial ...
Yonglin Mu +6 more
doaj +1 more source
Local authorities planning for urban sustainability - towards implementing energy conservation policies in development plan [PDF]
This study aims to examine lessons learned from local authorities in United Kingdom on how policies on energy conservation can be incorporated in their development plan.
Ho, Chin Siong
core
Year 1 report for ‘Conserving Texas Biodiversity: Status, Trends, and Conservation Planning for Fishes of Greatest Conservation Need’ [PDF]
State Wildlife Grant Program, grant TX T-106-1 (CFDA# 15.634), Contract No. 459125 UTA14-001402Substantive progress was made on all major Project Activities in this first year: Activity 1.
Casarez, Melissa +4 more
core +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Upland wetlands in the Namoi catchment : mapping distribution and disturbance classes of fens, bogs and lagoons [PDF]
To assist with planning and conservation strategies, mapping of wetlands above 700 m elevation across the Namoi Catchment (east of Tamworth) was undertaken.
Hunter, John T.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

