Results 51 to 60 of about 108,978 (310)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Operationalizing biodiversity for conservation planning
Journal of Biosciences, 2002 Biodiversity has acquired such a general meaning that people now find it difficult to pin down a precise sense for planning and policy-making aimed at biodiversity conservation. Because biodiversity is rooted in place, the task of conserving biodiversity should target places for conservation action; and because all places contain biodiversity, but not ...
Sahotra, Sarkar, Chris, Margules
openaire +2 more sources
LandAs cities struggle to balance affordable housing, sufficient public green space, climate change, and rising temperatures, the urgency for planners to integrate nature-based solutions into urban strategies is magnified.
Anita Walter +2 more
doaj +1 more source
European Countryside, 2018 Water retention in the landscape is discussed in the context of conservation and improvement of both its productive and non-productive functions. We analysed the retention potential of a small agricultural catchment associated with the Bílý potok brook ...
Doležal Petr +4 more
doaj +1 more source
, 2020 The conservation movement “Nature Needs Half” (NNH) aims to protect 50% of the earth by 2050. But increase in total protected area (PA) coverage alone does not guarantee adequate species protection, and identifying conservation priority areas that meet ...
Sheldon, Fran +2 more
core +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Survey methods for the purple martin in California
California Fish and Wildlife JournalThe purple martin (Progne subis) has declined substantially in numbers and geographic range since the 1980s. Surveys and monitoring are needed to better understand the status of the species, in order to set conservation priorities and direct actions ...
Daniel Airola
doaj +1 more source
Quantifying uncertainty in the identification of endangered ecological communities
Conservation Science and Practice, 2021 Ecological community and ecosystem “red lists” have been developed in several jurisdictions to improve ecosystem‐level biodiversity protection. However, a challenge for the conservation and management of listed ecosystems is consistent identification in ...
Josh Dorrough +4 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source