Results 41 to 50 of about 1,820,994 (309)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The sacred deer conflict of management after a 1000‐year history: Hunting in the name of conservation or loss of their genetic identity

Conservation Science and Practice
Human–wildlife conflict involves diverse stakeholders with conflicting values. Resolving such conflicts necessitates the development of management plans rooted in scientific knowledge and establishing of social consensus.
Toshihito Takagi, Harumi Torii, Shingo Kaneko, Hidetoshi B. Tamate   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

“This research is important for the conservation and Management of Sharks”: A proposed framework for ensuring that this is actually true

Conservation Science and Practice
Sharks and their relatives are ecologically important animals that face serious conservation challenges. Scientists studying chondrichthyans have expressed a desire to generate data that helps to conserve threatened species, but environmental advocates ...
D. S. Shiffman, T. Gupta, R. I. Braun, P. J. Lenihan, C. C. Macdonald   +4 more
doaj   +1 more source

ESTUDO QUÍMICO DE EFLORESCÊNCIAS SALINAS DO SÍTIO ARQUEOLÓGICO TOCA EXÚ DO JURUBEBA DO PARQUE NACIONAL SERRA DA CAPIVARA, PIAUÍ, BRASIL

Química Nova
Toca Exú do Jurubeba is part of a set of archaeological sites located in the Serra da Capivara National Park (Piauí, Brazil), a region of great world interest due to its archaeological potential, especially rock art.
Benedito Batista Farias Filho, Maria Conceição S. Meneses Lage, Rássius Alexandre Medeiros Lima   +2 more
doaj   +1 more source

The changing landscape of conservation science funding in the United States [PDF]

, 2010
To understand the changing role of funding sources in shaping conservation science in the United States, we analyzed acknowledgments from published studies, trends in research funding, and survey responses from conservation scientists.
Bakker, Victoria J., Baum, Julia K., Brodie, Jedediah F., Dickson, Brett G., Gibbs, Holly K., Jensen, Olaf P., McIntyre, Peter B., Salomon, Anne K.   +7 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Collaboration makes the master: Designing and implementing impact evaluations in Swiss parks

Conservation Science and Practice
Impact evaluation design and implementation require technical and methodological skills and funding. If the interest is in bridging the research–practice gap and mainstreaming its recommendations into decision‐making, then impact evaluations will require
Marina Cracco, Yanbing Wang, Marcel Hunziker, Lina Torregroza, Christian Ritzel   +4 more
doaj   +1 more source

Between Fakes, Forgeries, and Illicit Artifacts—Authenticity Studies in a Heritage Science Laboratory

Arts, 2018
Since its inauguration in 1888, the Rathgen Research Laboratory of the National Museums in Berlin has been challenged by authenticity questions on cultural heritage objects.
Stefan Simon, Stefan Röhrs
doaj   +1 more source

Conservation practice could benefit from routine testing and publication of management outcomes [PDF]

, 2013
Effective conservation requires a step change in the way practitioners can contribute to science and can have access to research outputs. The journal Conservation Evidence was established in 2004 to help practitioners surmount several obstacles they ...
Amano, Tatsya, Ausden, Malcolm, Beebee, Trevor J.C., Bullock, David, Daniels, Mike, Deutsch, James, Dicks, Lynn V., Griffiths, Richard A., Mitchell, Roger, Prior, Stephanie V., Sutherland, William J., Walsh, Jessica, Whitten, Tony   +12 more
core