Results 41 to 50 of about 56,540 (246)

Trends and future directions in the conservation social sciences

Conservation Biology
This special issue commemorates the 20th anniversary of the creation of the Society for Conservation Biology's Social Science Working Group (SSWG). In these two decades, the SSWG has grown into a global, interdisciplinary professional community. Our membership represents close to 60 countries and offers a home to a diverse group of social scientists ...
Vercammen, Ans, Banerjee, Sayan, Clifton, Kyle, Selinske, Matthew, Sandbrook, Chris   +4 more
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Social Effectiveness and Human-Wildlife Conflict: Linking the Ecological Effectiveness and Social Acceptability of Livestock Protection Tools

Frontiers in Conservation Science, 2021
Human-wildlife interactions are embedded within socio-ecological systems (SES), in which animal behavior and human decision-making reciprocally interact. While a growing body of research addresses specific social and ecological elements of human-wildlife
Lara Volski, Alex McInturff, Kaitlyn M. Gaynor, Kaitlyn M. Gaynor, Veronica Yovovich, Justin S. Brashares   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Social Sciences and landscape analysis: Opportunities for the improvement of conservation policy design

Journal of Environmental Management, 2008
This article develops a methodology aimed at generating a systematic social diagnosis of social and natural landscapes. The analytical process is divided into six easily replicable and causatively connected steps. The goal is two-fold: first, to present the inextricable connections between physical landscapes and the communities that occupy them.
Vaccaro Ribó, Ismael, Norman, Karma
openaire   +3 more sources

Navigating power in conservation

Conservation Science and Practice, 2023
Conservation research and practice are increasingly engaging with people and drawing on social sciences to improve environmental governance. In doing so, conservation engages with power in many ways, often implicitly.
Ross T. Shackleton, Gretchen Walters, Jevgeniy Bluwstein, Houria Djoudi, Livia Fritz, Flore Lafaye de Micheaux, Tristan Loloum, Van Thi Hai Nguyen, Mialy Rann Andriamahefazafy, Samantha S. Sithole, Christian A. Kull   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source