Results 31 to 40 of about 629,990 (269)

Does Treatment Modality Affect Clinical Results of Calcaneal Fractures: A Retrospective Comparative Study

Acta Medica Alanya, 2017
Aim: To determine if there is any difference in functional results between surgical and conservative treatments in displaced intra-articular fractures of the calcaneum.
Mehmet Nuri Konya, Serdar Sargın
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Conservative Management of Invasive Cervical Resorption: A Case Report

Journal of Pharmacy and Bioallied Sciences
“Invasive cervical resorption” (ICR) is a disorder that impacts the region of root surface that is present below the level of attachment of epithelium. Clinically, it manifests as a pink stain on the cervical part of the tooth.
Youssef Abdullah Algarni
doaj   +1 more source

Inventory of Patient-Reported Outcome Measures Used in the Non-Operative Care of Scoliosis: A Scoping Review

Children, 2023
It is unclear which patient-reported outcome measures (PROMs) can assess non-operative care for scoliosis. Most existing tools aim to assess the effects of surgery.
Eric C. Parent, Matthew Vaclavik, Cody Bourgoin, Courtney Hebert, Megan Bouwmeester, Sarah Cheslock, Rebecca Collins, Stefan Potgieter, Mark Coles, Sanja Schreiber, Sabrina Donzelli, Camille Warner   +11 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

The Influence of Domestic Politics of South Korea on its Relations with North Korea and the United States

JSP: Jurnal Ilmu Sosial dan Ilmu Politik, 2020
This paper aims to conduct research on the influence of domestic South Korean politics on relations with the United States and North Korea. In this case, the theory of dominance of domestic political actors explains where the dominance of a group will ...
Miftah Farid Darussalam
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Are local climate assemblies politically representative of the macro-public they represent, and does this matter?

Environmental Research Communications
Using the results of a follow-up survey circulated to the participants of the Herefordshire Citizens Climate Assembly (HCCA), I compare their stated political identity with the political makeup of the county of Herefordshire (the macro public from which ...
Rachel Coxcoon
doaj   +1 more source